Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.39 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22718633 | 0.88 | HDAC1 (0.49) | HDAC1EGLN2MEN1MAPTKMT2A | |
| SCHEMBL22718572 | 0.86 | TRPV1 (0.54) | HDAC1NR1H4TRPV1MEN1LMNA | |
| SCHEMBL22718538 | 0.85 | NPC1 (0.51) | HDAC1NR1H4TRPV1KDM4EMEN1 | |
| SCHEMBL22746508 | 0.85 | HDAC1 (0.46) | HDAC1NR1H4PDGFRBKDRITGB3 | |
| SCHEMBL22718553 | 0.83 | NR1H4 (0.60) | HDAC1NR1H4TRPV1MEN1KMT2A | |
| SCHEMBL22718596 | 0.83 | HDAC1 (0.46) | HDAC1NR1H4TRPV1KDM4EMEN1 | |
| SCHEMBL22718579 | 0.83 | KCNK3 (0.50) | HDAC1NR1H4KDM4EALDH1A1LMNA | |
| SCHEMBL22718821 | 0.78 | NR1H4 (0.55) | HDAC1NR1H4TRPV1SMN1; SMN2 | |
| SCHEMBL24601440 | 0.76 | HDAC1 (0.46) | HDAC1PDGFRBKDRTRPV1KDM4E | |
| SCHEMBL22718565 | 0.75 | TRPV1 (0.53) | HDAC1TRPV1MEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220213052-A1 | INHIBITORS OF RNA-BINDING PROTEINS, COMPOSITIONS THEREOF, AND THERAPEUTIC USES THEROF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2022-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220213052-A1 | INHIBITORS OF RNA-BINDING PROTEINS, COMPOSITIONS THEREOF, AND THERAPEUTIC USES THEROF | HNRNPF, RBM3, RBM15 | HDAC1 1875/4885NR1H4 1834/4885PDGFRB 3384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.