Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 14/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24601249 | 0.94 | ADORA3 (0.46) | ADORA3ADORA1ADORA2AADORA2BHTR2B | |
| SCHEMBL24600944 | 0.93 | ADORA3 (0.50) | ADORA3ADORA1ADORA2AADORA2BHTR2B | |
| SCHEMBL24600752 | 0.93 | ADORA3 (0.57) | ADORA3ADORA1ADORA2AADORA2BHTR2B | |
| SCHEMBL24600971 | 0.92 | ADORA3 (0.49) | ADORA3ADORA1ADORA2AADORA2BHTR2B | |
| SCHEMBL24600736 | 0.91 | ADORA3 (0.55) | ADORA3ADORA1ADORA2AADORA2BHTR2B | |
| SCHEMBL24600954 | 0.90 | ADORA3 (0.45) | ADORA3ADORA1ADORA2AADORA2BHTR2B | |
| SCHEMBL24600750 | 0.89 | ADORA3 (0.45) | ADORA3ADORA1ADORA2AADORA2BHTR2B | |
| SCHEMBL24600738 | 0.88 | ADORA3 (0.45) | ADORA3ADORA1ADORA2AADORA2BHTR2B | |
| SCHEMBL24601375 | 0.88 | ADORA3 (0.70) | ADORA3ADORA1ADORA2AADORA2BHTR2B | |
| SCHEMBL29762278 | 0.88 | ADORA3 (0.70) | ADORA3ADORA1ADORA2AADORA2BHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022143740-A1 | ADENOSINE A3 RECEPTOR AGONIST, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江春禾医药科技有限公司 | 2022-07-07 | — | — | WO | disclosed |