Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 11/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24600915 | 0.94 | KCNA5 (0.45) | KCNA5KCNH2ADORA3NT5EADORA2A | |
| SCHEMBL24600916 | 0.93 | KCNA5 (0.45) | KCNA5KCNH2ADORA3NT5EADORA2A | |
| SCHEMBL24600934 | 0.92 | KCNA5 (0.44) | KCNA5KCNH2ADORA3NT5EADORA2A | |
| SCHEMBL24601212 | 0.91 | ADORA3 (0.45) | KCNA5KCNH2ADORA3ADORA2AADORA1 | |
| SCHEMBL24600913 | 0.91 | KCNH2 (0.43) | KCNA5KCNH2ADORA3NT5EADORA2A | |
| SCHEMBL24601005 | 0.91 | ADORA3 (0.47) | KCNA5KCNH2ADORA3NT5EADORA2A | |
| SCHEMBL24601006 | 0.91 | ADORA3 (0.48) | ADORA3NT5EADORA2AADORA1ADORA2B | |
| SCHEMBL24601219 | 0.89 | ADORA3 (0.43) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL24601239 | 0.89 | ADORA3 (0.43) | KCNA5KCNH2ADORA3ADORA2AADORA1 | |
| SCHEMBL24600929 | 0.88 | ADORA3 (0.55) | ADORA3ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022143740-A1 | ADENOSINE A3 RECEPTOR AGONIST, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江春禾医药科技有限公司 | 2022-07-07 | — | — | WO | disclosed |