SCHEMBL24601409

SCHEMBL24601409

c1ccc2c(c1)oc1c(-c3ccc4c5c6c7ccc(-c8cccc9c8oc8ccccc89)cc7n7c8cc(-c9cccc%10c9oc9ccccc9%10)ccc8c(c8c9ccc(-c%10cccc%11c%10oc%10ccccc%10%11)cc9n(c4c3)c58)c67)cccc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.57
PRKDC P78527 6/20 0.47
GGPS1 O95749 1/20 0.43
PTGES2 Q9H7Z7 1/20 0.42
ATM Q13315 1/20 0.38
PRMT5 O14744 1/20 0.37
WDR77 Q9BQA1 1/20 0.37
PIK3CD O00329 1/20 0.36
PIK3CB P42338 1/20 0.36
AHR P35869 2/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
MAPT P10636 2/20 0.33
CYP2C19 P33261 1/20 0.33
CDC25A P30304 1/20 0.33
CDC25B P30305 1/20 0.33
CDC25C P30307 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22178599 0.97 ALOX5 (0.54) ALOX5PRKDCGGPS1PTGES2ATM
SCHEMBL22178469 0.90 ALOX5 (0.47) ALOX5PRKDCGGPS1PTGES2ATM
SCHEMBL22178727 0.90 ALOX5 (0.54) ALOX5PRKDCGGPS1PTGES2ATM
SCHEMBL24601413 0.89 ALOX5 (0.57) ALOX5PRKDCGGPS1PTGES2ATM
SCHEMBL22178726 0.84 ALOX5 (0.38) ALOX5PRKDCAHRMEN1KMT2A
SCHEMBL21473047 0.82 ALOX5 (0.49) ALOX5PRKDCGGPS1PTGES2ATM
SCHEMBL21473027 0.82 ALOX5 (0.49) ALOX5PRKDCGGPS1PTGES2ATM
SCHEMBL24601410 0.82 ALOX5 (0.36) ALOX5PRKDCAHRMEN1KMT2A
SCHEMBL24601806 0.82 ALOX5 (0.36) ALOX5PRKDCAHRMEN1KMT2A
SCHEMBL19541146 0.82 ALOX5 (0.54) ALOX5PRKDCGGPS1PTGES2ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES NCL, NOC2L, NOLC1 ALOX5 2351/4885PRKDC 3185/4885GGPS1 1093/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.