SCHEMBL24601485

SCHEMBL24601485

CC(C)(C)c1cc(-c2ccc3c4c5c6ccc(-c7cc(C(C)(C)C)cc(C(C)(C)C)c7)cc6n6c7cc(-c8cc(C(C)(C)C)cc(C(C)(C)C)c8)ccc7c(c7c8ccc(-c9cc(C(C)(C)C)cc(C(C)(C)C)c9)cc8n(c3c2)c47)c56)cc(C(C)(C)C)c1

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RXRB P28702 8/20 0.40
RXRA P19793 7/20 0.40
RXRG P48443 3/20 0.40
KDM4E B2RXH2 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
KIF11 P52732 1/20 0.31
CNR1 P21554 1/20 0.31
ICMT O60725 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24601347 0.95 RXRB (0.37) RXRBRXRARXRGKIF11ICMT
SCHEMBL24601483 0.94 RXRB (0.36) RXRBRXRARXRGICMT
SCHEMBL24601417 0.93 RXRB (0.36) RXRBRXRARXRGKDM4EMAPT
SCHEMBL24601345 0.93 RXRB (0.36) RXRBRXRARXRGKDM4EMAPT
SCHEMBL24601441 0.91 HTR1D (0.35) RXRBRXRARXRGICMT
SCHEMBL24601607 0.89 RXRB (0.33) RXRBRXRARXRG
SCHEMBL24601622 0.89 KIF11 (0.36) RXRBRXRARXRGKDM4EMAPT
SCHEMBL24601500 0.88 RXRB (0.36) RXRBRXRARXRGMAPTKIF11
SCHEMBL24601687 0.87 RXRB (0.40) RXRBRXRARXRGKDM4EGAA
SCHEMBL24601516 0.87 RXRB (0.35) RXRBRXRARXRGKIF11CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES NCL, NOC2L, NOLC1 RXRB 4748/4885RXRA 4654/4885RXRG 4587/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.