SCHEMBL24601508

SCHEMBL24601508

c1ccc(-c2ccc(-c3ccccc3)c(-c3ccc4c(c3)c3c5c6ccccc6n6c7ccc(-c8cc(-c9ccccc9)ccc8-c8ccccc8)cc7c(c7c8ccccc8n4c73)c56)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSPO P30536 1/20 0.37
MEN1 O00255 1/20 0.35
APAF1 O14727 1/20 0.35
NPC1 O15118 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
THRB P10828 1/20 0.35
XBP1 P17861 1/20 0.35
PTBP1 P26599 1/20 0.35
HTT P42858 1/20 0.35
RAB9A P51151 1/20 0.35
GALK1 P51570 1/20 0.35
BLM P54132 1/20 0.35
SMAD3 P84022 1/20 0.35
KMT2A Q03164 1/20 0.35
ATM Q13315 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22178719 1.00 TSPO (0.37) TSPOMEN1APAF1NPC1LMNA
SCHEMBL24601494 0.91 MAOB (0.35) MEN1APAF1NPC1LMNAMAPT
SCHEMBL24601426 0.91 MAOB (0.35) MEN1APAF1NPC1LMNAMAPT
SCHEMBL22178583 0.91 HSD17B10 (0.37) TSPOMEN1MAPTKMT2AHSD17B10
SCHEMBL22178510 0.89 TSPO (0.43) TSPOHSD17B10NR4A2PLA2G2APLA2G4A
SCHEMBL22178499 0.89 TSPO (0.43) TSPOHSD17B10NR4A2PLA2G2APLA2G4A
SCHEMBL24601804 0.87 TSPO (0.35) TSPOHSD17B10PIK3CAHTR6
SCHEMBL22178509 0.86 TSPO (0.41) TSPOMEN1KMT2ANR4A2PLA2G2A
SCHEMBL24601471 0.84 TSPO (0.39) TSPOMEN1LMNAMAPTHTT
SCHEMBL24601509 0.83 HSD17B10 (0.34) TSPOMEN1LMNAMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES NCL, NOC2L, NOLC1 TSPO 3404/4885MEN1 1635/4885APAF1 1011/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.