SCHEMBL24601528

SCHEMBL24601528

Cc1cccc(C)c1-c1cccc(-c2c(C)cccc2C)c1-c1ccc2c(c1)c1c3c4ccccc4n4c5ccc(-c6c(-c7c(C)cccc7C)cccc6-c6c(C)cccc6C)cc5c(c5c6ccccc6n2c51)c34

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NTRK1 P04629 1/20 0.39
ALKBH5 Q6P6C2 1/20 0.36
FTO Q9C0B1 1/20 0.36
MAPT P10636 3/20 0.36
KDM4E B2RXH2 1/20 0.36
FLT3 P36888 2/20 0.34
MYC P01106 1/20 0.33
ICMT O60725 2/20 0.32
TYMS P04818 1/20 0.32
NR3C1 P04150 1/20 0.32
PGR P06401 1/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
GAA P10253 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
PKM P14618 1/20 0.31
IDO1 P14902 1/20 0.31
MAPK1 P28482 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24601481 0.93 NTRK1 (0.39) NTRK1ALKBH5FTOMAPTKDM4E
SCHEMBL24601506 0.92 FLT3 (0.35) NTRK1ALKBH5FTOMAPTKDM4E
SCHEMBL22178500 0.87 NR3C1 (0.41) ALKBH5FTOMAPTKDM4EICMT
SCHEMBL24601480 0.85 FLT3 (0.34) NTRK1ALKBH5FTOMAPTKDM4E
SCHEMBL22178720 0.84 NR3C1 (0.37) ALKBH5FTOMAPTKDM4EFLT3
SCHEMBL24601649 0.84 HSD17B10 (0.36) MAPTKDM4EFLT3MEN1KMT2A
SCHEMBL24601430 0.84 HSD17B10 (0.36) MAPTKDM4EFLT3MEN1KMT2A
SCHEMBL22178733 0.82 NR3C1 (0.44) ICMTNR3C1PGRMEN1KMT2A
SCHEMBL24601509 0.82 HSD17B10 (0.34) MAPTKDM4EFLT3MEN1KMT2A
SCHEMBL24601459 0.81 CYP1A2 (0.40) ALKBH5FTOMAPTKDM4EFLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES NCL, NOC2L, NOLC1 NTRK1 3178/4885ALKBH5 580/4885FTO 1886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.