SCHEMBL24601533

SCHEMBL24601533

c1ccc(-c2ccc3c(c2)c2c4c5ccc(-c6ccccc6)cc5n5c6ccc(-c7ccccc7)cc6c(c6c7ccc(-c8ccccc8)cc7n3c26)c45)cc1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.40
LIMK1 P53667 1/20 0.38
TSPO P30536 1/20 0.36
NR4A2 P43354 2/20 0.35
LDHA P00338 2/20 0.34
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
NR3C1 P04150 1/20 0.34
SERPINE1 P05121 1/20 0.34
JAK2 O60674 2/20 0.33
ALOX5 P09917 1/20 0.33
GRM2 Q14416 1/20 0.33
BRD4 O60885 1/20 0.33
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
HTR6 P50406 2/20 0.33
FEN1 P39748 1/20 0.33
PLA2G2A P14555 1/20 0.33
PLA2G4A P47712 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24601471 0.93 TSPO (0.39) MAOBLIMK1TSPONR4A2LDHA
SCHEMBL24601466 0.93 MAOB (0.44) MAOBLIMK1LDHAESR1ESR2
SCHEMBL22178510 0.91 TSPO (0.43) MAOBTSPONR4A2LDHANR3C1
SCHEMBL22178597 0.91 MAOB (0.41) MAOBLIMK1TSPOLDHAESR1
SCHEMBL22178499 0.91 TSPO (0.43) MAOBTSPONR4A2LDHANR3C1
SCHEMBL24601501 0.90 MAOB (0.35) MAOBLIMK1TSPONR4A2ESR1
SCHEMBL24601519 0.90 MAOB (0.35) MAOBLIMK1TSPONR4A2ESR1
SCHEMBL22178509 0.88 TSPO (0.41) MAOBTSPONR4A2LDHAESR1
SCHEMBL24601437 0.88 MAOB (0.39) MAOBLIMK1TSPOLDHAESR1
SCHEMBL24601658 0.86 TSPO (0.36) TSPOESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES NCL, NOC2L, NOLC1 MAOB 2002/4885LIMK1 1209/4885TSPO 3404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.