SCHEMBL24601642

SCHEMBL24601642

CC(C)(C)c1ccc2c3c4c5ccc(-c6c(-c7ccccc7)cccc6-c6ccccc6)cc5n5c6cc(C(C)(C)C)ccc6c(c6c7ccccc7n(c2c1)c36)c45

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.34
DNMT1 P26358 3/20 0.33
KIF11 P52732 2/20 0.33
SERPINE1 P05121 3/20 0.32
ALDH1A1 P00352 2/20 0.32
MAPT P10636 2/20 0.32
MAPK1 P28482 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
NR1H4 Q96RI1 2/20 0.32
HSD17B10 Q99714 1/20 0.32
NPC1 O15118 1/20 0.31
PLA2G1B P04054 1/20 0.31
NFKB1 P19838 1/20 0.31
CASP3 P42574 1/20 0.31
RAB9A P51151 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24601645 0.97 GPR84 (0.34) GPR84DNMT1KIF11SERPINE1ALDH1A1
SCHEMBL24601644 0.97 DNMT1 (0.35) GPR84DNMT1KIF11SERPINE1ALDH1A1
SCHEMBL24601478 0.96 DNMT1 (0.35) GPR84DNMT1KIF11SERPINE1ALDH1A1
SCHEMBL24601479 0.94 DNMT1 (0.36) GPR84DNMT1KIF11SERPINE1ALDH1A1
SCHEMBL24601482 0.94 SERPINE1 (0.34) GPR84DNMT1KIF11SERPINE1ALDH1A1
SCHEMBL24601643 0.92 DNMT1 (0.36) GPR84DNMT1KIF11SERPINE1ALDH1A1
SCHEMBL24601785 0.89 GPR84 (0.34) GPR84SERPINE1ALDH1A1MAPTMAPK1
SCHEMBL24601563 0.89 GPR84 (0.34) GPR84DNMT1KIF11SERPINE1ALDH1A1
SCHEMBL24601423 0.89 HSD17B10 (0.35) ALDH1A1MAPTHSD17B10KDM4EMEN1
SCHEMBL24601624 0.89 HSD17B10 (0.35) ALDH1A1MAPTHSD17B10KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES NCL, NOC2L, NOLC1 GPR84 4574/4885DNMT1 333/4885KIF11 3347/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.