SCHEMBL24601670

SCHEMBL24601670

CC(C)(C)c1cc(-c2cccc3c4c5c6cc(-c7ccc(F)cc7)ccc6n6c7c(-c8cc(C(C)(C)C)cc(C(C)(C)C)c8)cccc7c(c7c8cc(-c9ccc(F)cc9)ccc8n(c23)c74)c56)cc(C(C)(C)C)c1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 3/20 0.33
PGR P06401 1/20 0.33
ICMT O60725 1/20 0.32
KCNH2 Q12809 1/20 0.31
RXRA P19793 2/20 0.30
RXRB P28702 2/20 0.30
KIF11 P52732 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24601671 0.92 ICMT (0.39) NR3C1PGRICMTRXRARXRB
SCHEMBL24601577 0.92 SERPINE1 (0.35) ICMTRXRARXRBKIF11
SCHEMBL24601763 0.92 DHODH (0.33) KCNH2
SCHEMBL24601585 0.92 RXRB (0.36) ICMTRXRARXRBKIF11
SCHEMBL24601832 0.91 RXRB (0.36) RXRARXRBKIF11
SCHEMBL24601558 0.90 ICMT (0.35) NR3C1PGRICMTKIF11
SCHEMBL24601663 0.89
SCHEMBL24601665 0.88 SCD (0.35) PGRICMT
SCHEMBL24601559 0.88 ICMT (0.38) NR3C1PGRICMT
SCHEMBL24601742 0.86 DNMT1 (0.34) PGRRXRARXRBKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES NCL, NOC2L, NOLC1 NR3C1 3883/4885PGR 2243/4885ICMT 174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.