SCHEMBL24601674

SCHEMBL24601674

CC(C)(C)c1cc(-c2ccc(C=O)c(Cl)c2)cc(C(C)(C)C)c1

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.47
RXRB P28702 8/20 0.44
RXRA P19793 7/20 0.44
RXRG P48443 3/20 0.44
AKR1C2 P52895 1/20 0.40
AKR1C1 Q04828 1/20 0.40
CNR1 P21554 1/20 0.39
ERN1 O75460 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31426981 1.00 TDP1 (0.47) TDP1RXRBRXRARXRGAKR1C2
SCHEMBL11872397 0.82 TDP1 (0.67) TDP1ERN1
SCHEMBL4057549 0.80 TDP1 (0.55) TDP1RXRBRXRARXRGAKR1C2
SCHEMBL8035343 0.75 TDP1 (0.53) TDP1AKR1C2AKR1C1ERN1
SCHEMBL609449 0.74 TDP1 (0.69) TDP1ERN1
SCHEMBL1547171 0.73 TDP1 (0.55) TDP1AKR1C2AKR1C1ERN1
SCHEMBL5181460 0.72 TDP1 (0.53) TDP1ERN1
SCHEMBL4526927 0.71 RXRB (0.65) RXRBRXRARXRGAKR1C2AKR1C1
SCHEMBL414084 0.71 RXRB (0.65) RXRBRXRARXRGAKR1C2AKR1C1
SCHEMBL22870844 0.70 RXRB (0.55) RXRBRXRARXRGAKR1C2AKR1C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260052832-A1 COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2026-02-19 US disclosed
EP-4450589-B1 BLUE LUMINESCENT COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2025-11-19 EP disclosed
US-20240365663-A1 BLUE LUMINESCENT COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2024-10-31 US disclosed
EP-4450589-A1 BLUE LUMINESCENT COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE Samsung Electronics Co., Ltd. (KR) 2024-10-23 EP disclosed
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES NCL, NOC2L, NOLC1 TDP1 1105/4885RXRB 4748/4885RXRA 4654/4885
US-20260052832-A1 COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE ETV1, L1CAM, CCNT1 TDP1 1276/4885RXRB 4040/4885RXRA 4202/4885
US-20240365663-A1 BLUE LUMINESCENT COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE TYR, IK, CYBA TDP1 3962/4885RXRB 3396/4885RXRA 3821/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.