Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31426976 | 0.84 | TDP1 (0.41) | TDP1CYP2C19ALDH1A1MAPTGAA | |
| SCHEMBL20379836 | 0.84 | TDP1 (0.41) | TDP1CYP2C19ALDH1A1MAPTGAA | |
| SCHEMBL11330982 | 0.83 | TTR (0.48) | TDP1CYP2C19ALDH1A1MAPTGAA | |
| SCHEMBL11882755 | 0.83 | TTR (0.48) | TDP1CYP2C19ALDH1A1MAPTGAA | |
| SCHEMBL356134 | 0.81 | MAPT (0.44) | TDP1CYP2C19ALDH1A1MAPTGAA | |
| SCHEMBL24601674 | 0.80 | TDP1 (0.47) | TDP1RXRARXRBRXRGAKR1C2 | |
| SCHEMBL4068070 | 0.80 | TDP1 (0.47) | TDP1CYP2C19ALDH1A1MAPTGAA | |
| SCHEMBL31426981 | 0.80 | TDP1 (0.47) | TDP1RXRARXRBRXRGAKR1C2 | |
| SCHEMBL952008 | 0.80 | TDP1 (0.55) | TDP1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3146888 | 0.80 | ALDH1A1 (0.43) | TDP1CYP2C19ALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1390336-A1 | METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS | DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) | 2004-02-25 | — | — | EP | claimed |
| WO-2002096849-A1 | METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2002-12-05 | — | — | WO | claimed |
| US-20220213113-A1 | NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2022-07-07 | — | — | US | disclosed |
| CN-100577651-C | Lactam compound and medicinal use thereof | AJINOMOTO KK | 2010-01-06 | — | — | CN | disclosed |
| US-7632830-B2 | Lactam compounds and pharmaceutical use thereof | AJINOMOTO CO., INC. (JP) | 2009-12-15 | — | — | US | disclosed |
| EP-1346993-B1 | LACTAM COMPOUNDS AND MEDICAL USE THEREOF | AJINOMOTO KK (JP) | 2009-10-21 | — | — | EP | disclosed |
| US-20090134785-A1 | ORGANOMETALLIC COMPLEX, ORGANIC LIGHT-EMITTING ELEMENT USING SAME, AND DISPLAY DEVICE | CANON KABUSHIKI KAISHA (JP) | 2009-05-28 | — | — | US | disclosed |
| US-20090134785-A1 | ORGANOMETALLIC COMPLEX, ORGANIC LIGHT-EMITTING ELEMENT USING SAME, AND DISPLAY DEVICE | CANON KABUSHIKI KAISHA (JP) | 2009-05-28 | — | — | US | disclosed |
| US-20080096862-A1 | LACTAM COMPOUNDS AND PHARMACEUTICAL USE THEREOF | AJINOMOTO CO., INC. (JP) | 2008-04-24 | — | — | US | disclosed |
| US-7326701-B2 | Lactam compounds and pharmaceutical use thereof | AJINOMOTO CO., INC. (JP) | 2008-02-05 | — | — | US | disclosed |
| CN-1911915-A | Lactam compound and medicinal use thereof | AJINOMOTO KK (JP) | 2007-02-14 | — | — | CN | disclosed |
| US-7153850-B2 | Lactam compounds and pharmaceutical use thereof | AJINOMOTO CO., INC. (JP) | 2006-12-26 | — | — | US | disclosed |
| US-20060189597-A1 | Lactam compounds and pharmaceutical use thereof | AJINOMOTO CO., INC. (JP) | 2006-08-24 | — | — | US | disclosed |
| CN-1269818-C | Lactam compounds and pharmaceutical use thereof | AJINOMOTO KK (JP) | 2006-08-16 | — | — | CN | disclosed |
| CN-1487940-A | Lactam compounds and pharmaceutical use thereof | ֮����ʽ���� | 2004-04-07 | — | — | CN | disclosed |
| US-20040048847-A1 | Lactam compounds and pharmaceutical use thereof | AJINOMOTO CO. INC (JP) | 2004-03-11 | — | — | US | disclosed |
| EP-1390336-A1 | METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS | DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) | 2004-02-25 | — | — | EP | disclosed |
| EP-1346993-A1 | LACTAM COMPOUNDS AND MEDICINAL USE THEREOF | Ajinomoto Co., Inc. (JP) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002096849-A1 | METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2002-12-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189597-A1 | Lactam compounds and pharmaceutical use thereof | SLC2A4, SLC2A8, SLC2A1 | TDP1 4390/4885CYP2C19 2211/4885ALDH1A1 911/4885 |
| US-20220213113-A1 | NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | NCL, NOC2L, NOLC1 | TDP1 1105/4885CYP2C19 4124/4885ALDH1A1 3824/4885 |
| US-20040048847-A1 | Lactam compounds and pharmaceutical use thereof | SLC2A4, SLC2A8, SLC2A1 | TDP1 4390/4885CYP2C19 2211/4885ALDH1A1 911/4885 |
| US-20090134785-A1 | ORGANOMETALLIC COMPLEX, ORGANIC LIGHT-EMITTING ELEMENT USING SAME, AND DISPLAY DEVICE | MNS1, NOM1, AP3M1 | TDP1 2487/4885CYP2C19 3929/4885ALDH1A1 1348/4885 |
| US-20080096862-A1 | LACTAM COMPOUNDS AND PHARMACEUTICAL USE THEREOF | SLC2A4, SLC2A8, SLC2A1 | TDP1 4390/4885CYP2C19 2211/4885ALDH1A1 911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.