Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16789802 | 0.80 | KDM4E (0.38) | KDM4EALDH1A1LMNASMN1; SMN2NPC1 | |
| SCHEMBL17561708 | 0.80 | KDM4E (0.38) | KDM4EALDH1A1LMNANPC1RAB9A | |
| SCHEMBL1285587 | 0.80 | NQO2 (0.41) | KDM4EALDH1A1LMNASMN1; SMN2NPC1 | |
| SCHEMBL1701419 | 0.80 | CDK9 (0.38) | KDM4EALDH1A1LMNANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL1285502 | 0.79 | KDM4E (0.39) | KDM4EALDH1A1LMNANPC1RAB9A | |
| SCHEMBL16448858 | 0.73 | NOX1 (0.33) | KDM4EALDH1A1LMNA | |
| SCHEMBL16789776 | 0.73 | KDM4E (0.33) | KDM4EALDH1A1LMNA | |
| SCHEMBL15840303 | 0.73 | ELANE (0.41) | KDM4EALDH1A1LMNASMN1; SMN2NPC1 | |
| SCHEMBL21769584 | 0.71 | NPC1 (0.38) | KDM4EALDH1A1LMNANUDT1NPC1 | |
| SCHEMBL22502908 | 0.71 | KDM4E (0.36) | KDM4EALDH1A1LMNAMAPTCDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220212183-A1 | CROSS-LINKED HIGH STABLE ANION EXCHANGE BLEND MEMBRANES WITH POLYETHYLENEGLYCOLS AS HYDROPHILIC MEMBRANE PHASE | HAERING THOMAS (DE) | 2022-07-07 | — | — | US | disclosed |