SCHEMBL24602686

SCHEMBL24602686

CC(C)(C)OC(=O)N1Cc2ccc(Cl)nc2CC1C=O

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ ABHD6 Q9BV23 1/20 0.42
▸ HDAC8 Q9BY41 9/20 0.37
▸ PTPN1 P18031 4/20 0.37
▸ ESR2 Q92731 1/20 0.37
▸ NR1H2 P55055 1/20 0.36
▸ NAMPT P43490 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30685431 1.00 MEN1 (0.43) MEN1KMT2AABHD6HDAC8PTPN1
SCHEMBL24602628 0.90 ABHD6 (0.40) MEN1KMT2AABHD6HDAC8PTPN1
SCHEMBL26914843 0.85 MEN1 (0.47) MEN1KMT2AABHD6HDAC8PTPN1
SCHEMBL31621613 0.84 MEN1 (0.41) MEN1KMT2AABHD6HDAC8PTPN1
SCHEMBL31621568 0.84 MEN1 (0.41) MEN1KMT2AABHD6HDAC8PTPN1
SCHEMBL24602711 0.84 MEN1 (0.41) MEN1KMT2AABHD6HDAC8PTPN1
SCHEMBL24602685 0.83 ABHD6 (0.42) MEN1KMT2AABHD6HDAC8PTPN1
SCHEMBL26914866 0.82 ABHD6 (0.36) MEN1KMT2AABHD6HDAC8PTPN1
SCHEMBL31621607 0.82 ABHD6 (0.44) MEN1KMT2AABHD6HDAC8PTPN1
SCHEMBL31621630 0.82 ABHD6 (0.44) MEN1KMT2AABHD6HDAC8PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115703776-B Plasmin inhibitor, preparation method and application thereof 赛诺哈勃药业(成都)有限公司 2025-06-17 — — CN disclosed
US-20240300986-A1 PLASMIN INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF SCINNOHUB PHARMACEUTICAL CO., LTD (CN) 2024-09-12 — — US disclosed
US-20240124443-A1 PLASMIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF SCINNOHUB PHARMACEUTICAL CO., LTD (CN) 2024-04-18 — — US disclosed
EP-4289850-A1 PLASMIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF Scinnohub Pharmaceutical Co., Ltd (CN) 2023-12-13 — — EP disclosed
EP-4289850-A1 PLASMIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF Scinnohub Pharmaceutical Co., Ltd (CN) 2023-12-13 — — EP disclosed
EP-4273135-A1 PLASMIN INHIBITOR, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Scinnohub Pharmaceutical Co., Ltd (CN) 2023-11-08 — — EP disclosed
EP-4273135-A1 PLASMIN INHIBITOR, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Scinnohub Pharmaceutical Co., Ltd (CN) 2023-11-08 — — EP disclosed
CN-116848122-A Plasmin inhibitor, preparation method and application thereof 赛诺哈勃药业(成都)有限公司 2023-10-03 — — CN disclosed
CN-116710440-A Plasmin inhibitor, preparation method and application thereof 赛诺哈勃药业(成都)有限公司 2023-09-05 — — CN disclosed
WO-2022166845-A1 PLASMIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 赛诺哈勃药业(成都)有限公司 2022-08-11 — — WO disclosed
WO-2022143911-A1 PLASMIN INHIBITOR, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 赛诺哈勃药业(成都)有限公司 2022-07-07 — — WO disclosed
WO-2022143911-A1 PLASMIN INHIBITOR, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 赛诺哈勃药业(成都)有限公司 2022-07-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240124443-A1 PLASMIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF F2, PLG, PLAT MEN1 726/4885KMT2A 2898/4885ABHD6 2535/4885
US-20240300986-A1 PLASMIN INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF F2, PLG, PLAT MEN1 993/4885KMT2A 3791/4885ABHD6 3009/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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