SCHEMBL246027

SCHEMBL246027

C#CCC(O)C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2498379 1.00
SCHEMBL6129575 0.77
SCHEMBL1332932 0.77
SCHEMBL6129550 0.77
SCHEMBL3092130 0.77 GRIK1 (0.48)
SCHEMBL7706660 0.76
SCHEMBL2759245 0.76
SCHEMBL17212018 0.74 GRIK1 (0.46)
SCHEMBL379205 0.74 GRIK1 (0.64)
SCHEMBL28850932 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2516413-B1 PROCESS FOR PREPARING CYCLIC ESTERS COMPRISING UNSATURATED FUNCTIONAL GROUPS AND POLYESTERS PREPARED FROM SAME EVONIK CORP (US) 2016-04-13 EP claimed
CN-103003260-A Process for preparing cyclic esters containing unsaturated functional groups and polyesters prepared therefrom SURMODICS PHARMACEUTICALS INC 2013-03-27 CN claimed
US-8399686-B2 Process for preparing cyclic esters comprising unsaturated functional groups and polyesters prepared from same EVONIK DEGUSSA CORPORATION (US) 2013-03-19 US claimed
EP-2516413-A1 PROCESS FOR PREPARING CYCLIC ESTERS COMPRISING UNSATURATED FUNCTIONAL GROUPS AND POLYESTERS PREPARED FROM SAME Evonik Degussa Corporation (US) 2012-10-31 EP claimed
US-20120004324-A1 Process for Preparing Cyclic Esters Comprising Unsaturated Functional Groups and Polyesters Prepared From Same EVONIK OPERATIONS GMBH (DE) 2012-01-05 US claimed
WO-2011084466-A1 PROCESS FOR PREPARING CYCLIC ESTERS COMPRISING UNSATURATED FUNCTIONAL GROUPS AND POLYESTERS PREPARED FROM SAME SURMODICS PHARMACEUTICALS, INC. (US) 2011-07-14 WO claimed
WO-2017082827-A1 ENGINEERING STRUCTURALLY DEFINED NON-SACCHARIDE GLYCOSAMINOGLYCAN MIMETICS VIA A POLYPROLINE SCAFFOLD AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2017-05-18 WO disclosed
EP-2516413-B1 PROCESS FOR PREPARING CYCLIC ESTERS COMPRISING UNSATURATED FUNCTIONAL GROUPS AND POLYESTERS PREPARED FROM SAME EVONIK CORP (US) 2016-04-13 EP disclosed
US-8927682-B2 Functionalization of polyglycolides by “click” chemistry BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2015-01-06 US disclosed
US-8758828-B2 Process for preparing cyclic esters comprising unsaturated functional groups and polyesters prepared from same EVONIK CORPORATION (US) 2014-06-24 US disclosed
US-20130171261-A1 Process for Preparing Cyclic Esters Comprising Unsaturated Functional groups And Polyesters Prepared From Same EVONIK DEGUSSA CORPORATION (US) 2013-07-04 US disclosed
CN-103003260-A Process for preparing cyclic esters containing unsaturated functional groups and polyesters prepared therefrom SURMODICS PHARMACEUTICALS INC 2013-03-27 CN disclosed
US-8399686-B2 Process for preparing cyclic esters comprising unsaturated functional groups and polyesters prepared from same EVONIK DEGUSSA CORPORATION (US) 2013-03-19 US disclosed
WO-2009029242-A1 FUNCTIONALIZATION OF POLYGLYCOLIDES BY 'CLICK' CHEMISTRY MICHIGAN STATE UNIVERSITY (US) 2009-03-05 WO disclosed
US-20090054619-A1 Functionalization of polyglycolides by \"click\" chemistry BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2009-02-26 US disclosed
US-20090054619-A1 Functionalization of polyglycolides by \"click\" chemistry BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2009-02-26 US disclosed
US-20080318923-A1 1,3-Dihydro-2H-Indole-2-One Compound and Pyrrolidine-2-One Compound Fused With Aromatic Heterocycle TAISHO PHARMACEUTICAL CO., LTD. (JP) 2008-12-25 US disclosed
WO-2008031157-A1 ACETYLENIC COMPOUNDS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2008-03-20 WO disclosed
WO-2008031157-A1 ACETYLENIC COMPOUNDS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2008-03-20 WO disclosed
US-6610730-B2 Viricides; protease inbhibitor AGOURON PHARMACEUTICALS, INC. 2003-08-26 US disclosed