Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 5/20 | 0.64 |
| ▸ | GRIK2 | Q13002 | 5/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6870462 | 0.87 | — | — | |
| SCHEMBL28591034 | 0.85 | — | — | |
| SCHEMBL3104177 | 0.85 | — | — | |
| SCHEMBL5053789 | 0.81 | CHRM1 (0.62) | GRIK1GRIK2HDAC1HDAC2CHRM1 | |
| SCHEMBL7557794 | 0.81 | CHRM1 (0.62) | GRIK1GRIK2HDAC1HDAC2CHRM1 | |
| SCHEMBL7550179 | 0.81 | GRIK1 (0.62) | GRIK1GRIK2HDAC1HDAC2CHRM1 | |
| SCHEMBL8847145 | 0.81 | GRIK1 (0.52) | GRIK1GRIK2HDAC1HDAC2CHRM1 | |
| SCHEMBL28435149 | 0.81 | FOLH1 (0.56) | GRIK1GRIK2FOLH1CYP2D6MAPT | |
| SCHEMBL8847127 | 0.79 | GRIK1 (0.50) | GRIK1GRIK2HDAC1HDAC2CHRM1 | |
| SCHEMBL15310777 | 0.79 | GRIK1 (1.00) | GRIK1GRIK2SLC1A1SLC1A2SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986716-B | Medium-high voltage special cable material and preparation method thereof | 南方珠江科技有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-117986716-A | Medium-high voltage special cable material and preparation method thereof | 南方珠江科技有限公司 | 2024-05-07 | — | — | CN | claimed |
| CN-104910328-B | Fluorine-containing high dielectric property polynorbornene class-poly-(1,6-heptadiyne) based block copolymer and preparation method thereof | 华东师范大学 | 2017-01-04 | — | — | CN | claimed |
| CN-104403103-B | Hyperbranched poly triazole hb-PTA-OEG and its preparation method and application | 华东师范大学 | 2016-06-29 | — | — | CN | claimed |
| CN-105085756-A | Conjugated polyacetylene containing perylene bisimide and preparation method thereof | UNIV EAST CHINA NORMAL | 2015-11-25 | — | — | CN | claimed |
| CN-104910328-A | Fluorine-containing high-dielectricity polynorbornene-poly(1,6-heptadiyne) block copolymer and preparation method thereof | UNIV EAST CHINA NORMAL | 2015-09-16 | — | — | CN | claimed |
| CN-104403103-A | Hyperbranched polytriazole hb-PTA-OEG, and preparation method and application thereof | UNIV EAST CHINA NORMAL | 2015-03-11 | — | — | CN | claimed |
| US-12503553-B2 | Biodegradable drug-polymer conjugate | POLYACTIVA PTY LTD (AU) | 2025-12-23 | — | — | US | disclosed |
| US-20240247106-A1 | BIODEGRADABLE DRUG-POLYMER CONJUGATE | POLYACTIVA PTY LTD (AU) | 2024-07-25 | — | — | US | disclosed |
| EP-2964224-B1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | POLYACTIVA PTY LTD (AU) | 2024-07-03 | — | — | EP | disclosed |
| EP-2964224-B1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | POLYACTIVA PTY LTD (AU) | 2024-07-03 | — | — | EP | disclosed |
| CN-117986716-B | Medium-high voltage special cable material and preparation method thereof | 南方珠江科技有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-117986716-A | Medium-high voltage special cable material and preparation method thereof | 南方珠江科技有限公司 | 2024-05-07 | — | — | CN | disclosed |
| US-20100029888-A1 | Click-Reaction Crosslinkable Multicomponent Silicone Compositions | WACKER CHEMIE AG (DE) | 2010-02-04 | — | — | US | disclosed |
| CN-1166622-C | 2-amino-1, 2-indanes as selective dopamine D3 ligands | �������Ŷ���Լ��������˾ | 2004-09-15 | — | — | CN | disclosed |
| EP-0807101-B1 | 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS | UPJOHN CO (US) | 2001-06-13 | — | — | EP | disclosed |
| US-5936000-A | 2-aminoindans as selective dopamine D3 ligands | PHARMACIA & UPJOHN COMPANY (US) | 1999-08-10 | — | — | US | disclosed |
| CN-1172469-A | 2 -aminoindans as selective dopamine D3 ligands | UPJOHN CO (US) | 1998-02-04 | — | — | CN | disclosed |
| EP-0807101-A1 | 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 1997-11-19 | — | — | EP | disclosed |
| WO-1996023760-A1 | 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 1996-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240247106-A1 | BIODEGRADABLE DRUG-POLYMER CONJUGATE | ADRB3, PTGER3, CHRNE | GRIK1 1826/4885GRIK2 2332/4885HDAC1 1701/4885 |
| US-12503553-B2 | Biodegradable drug-polymer conjugate | ADRB3, PTGER3, CHRNE | GRIK1 1826/4885GRIK2 2332/4885HDAC1 1701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.