SCHEMBL2460591

SCHEMBL2460591

CCCCN(CCCC)c1[c]cccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.37
ELANE P08246 1/20 0.36
NPSR1 Q6W5P4 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
UTS2R Q9UKP6 1/20 0.35
MAPT P10636 2/20 0.33
NR1H2 P55055 1/20 0.33
NR1H3 Q13133 1/20 0.33
OPRM1 P35372 1/20 0.33
OPRL1 P41146 1/20 0.33
LMNA P02545 1/20 0.33
MAPK1 P28482 1/20 0.33
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 2/20 0.33
GAA P10253 2/20 0.33
AR P10275 1/20 0.33
POLB P06746 1/20 0.33
HTT P42858 2/20 0.33
KCNH2 Q12809 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4719826 0.96 TDP1 (0.35) TDP1ELANENPSR1MEN1KMT2A
SCHEMBL1077660 0.94 KCNH2 (0.38) TDP1ELANEOPRM1ALDH1A1KCNH2
SCHEMBL8643073 0.93 KCNH2 (0.40) OPRM1ALDH1A1KCNH2CNR2
SCHEMBL9800560 0.93 KCNH2 (0.40) OPRM1ALDH1A1KCNH2CNR2
SCHEMBL9800595 0.93 KCNH2 (0.40) OPRM1ALDH1A1KCNH2CNR2
SCHEMBL2460597 0.93 KCNH2 (0.40) OPRM1ALDH1A1KCNH2CNR2
SCHEMBL2456294 0.93 MAPT (0.36) TDP1ELANENPSR1MEN1KMT2A
SCHEMBL816702 0.88 TP53 (0.34) KCNH2
SCHEMBL2459640 0.86 KCNH2 (0.41) OPRM1ALDH1A1KCNH2CNR2
SCHEMBL2448855 0.83 MAPT (0.37) TDP1NPSR1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0884367-B1 Light-writable data storage media containing cationic diphenylamine dyes BAYER AG (DE) 2003-08-13 EP claimed
US-5952475-A CATIONIC THIADIAZOLEDIPHENYLAMINE DYES FOR USE IN INKJET PRINTING AND IN LIGHT-WRITABLE DATA STORAGE MEDIA AND IN DYE TRANSFER FILMS BAYER AKTIENGESELLSCHAFT (DE) 1999-09-14 US claimed
EP-0884367-A2 Cationic diphenylamine dyestuffs and their anhydrobases BAYER AG (DE) 1998-12-16 EP claimed
US-4454211-A Electrophotographic photosensitive member with pyrazoline charge transport material CANON KABUSHIKI KAISHA (JP) 1984-06-12 US claimed
US-4214093-A PROTEOLYTIC ENZYME INHIBITORS TORII & CO., LTD. (JP) 1980-07-22 US claimed
EP-3172203-A1 MOLECULES PRESENTING DUAL EMISSION PROPERTIES Université de Strasbourg (FR) 2017-05-31 EP disclosed
EP-2514402-B1 PREVENTING OR AMELIORATING AGENT FOR PIGMENTATION POLA CHEM IND INC (JP) 2016-08-31 EP disclosed
US-9414998-B2 Preventing or ameliorating agent for pigmentation POLA CHEMICAL INDUSTRIES INC. (JP) 2016-08-16 US disclosed
WO-2016012457-A1 MOLECULES PRESENTING DUAL EMISSION PROPERTIES UNIVERSITÉ DE STRASBOURG (FR) 2016-01-28 WO disclosed
US-9163046-B2 Process for producing substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-10-20 US disclosed
US-20140322150-A1 PREVENTING OR AMELIORATING AGENT FOR PIGMENTATION POLA CHEMICAL INDUSTRIES INC. (JP) 2014-10-30 US disclosed
EP-2514402-A1 PROPHYLACTIC OR AMELIORATING AGENT FO PIGMENTATION Pola Chemical Industries Inc. (JP) 2012-10-24 EP disclosed
US-4434109-A STABILIZERS AGAINST HEAT, OXYGEN AND LIGHT CIBA-GEIGY CORPORATION (US) 1984-02-28 US disclosed
EP-0042359-A1 Phosphonous-acid monoester monoamide and organic polymers stabilized therewith CIBA-GEIGY AG (CH) 1981-12-23 EP disclosed
US-4256458-A DIMERIC PYRIDINIUM DYES BASF AKTIENGESELLSCHAFT (DE) 1981-03-17 US disclosed
US-4214093-A PROTEOLYTIC ENZYME INHIBITORS TORII & CO., LTD. (JP) 1980-07-22 US disclosed
US-4187226-A 1-(ALKOXYALKYLSULFONYLPHENYL/-3-PHENYLPYRAZOLINES, OPTICAL BRIGHTENERS BASF AKTIENGESELLSCHAFT (DE) 1980-02-05 US disclosed
US-4183851-A OPTICAL BRIGHTENERS BASF AKTIENGESELLSCHAFT (DE) 1980-01-15 US disclosed
US-4164500-A OPTICAL BRIGHTENERS BASF AKTIENGESELLSCHAFT (DE) 1979-08-14 US disclosed
US-4129563-A OPTICAL BRIGHTENERS BASF AKTIENGESELLSCHAFT (DE) 1978-12-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140322150-A1 PREVENTING OR AMELIORATING AGENT FOR PIGMENTATION TYR, MC1R, MITF TDP1 4054/4885ELANE 535/4885NPSR1 2899/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.