Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.45 |
| ▸ | MARS1 | P56192 | 2/20 | 0.32 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.32 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.32 |
| ▸ | POLRMT | O00411 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24312529 | 1.00 | TMPRSS2 (0.45) | TMPRSS2MARS1TRPM2RIPK1SLC15A1 | |
| SCHEMBL25609908 | 0.91 | TMPRSS2 (0.44) | TMPRSS2RIPK1POLRMT | |
| SCHEMBL25910110 | 0.91 | TMPRSS2 (0.44) | TMPRSS2RIPK1POLRMT | |
| SCHEMBL24312576 | 0.90 | TMPRSS2 (0.43) | TMPRSS2RIPK1POLRMT | |
| SCHEMBL24606269 | 0.89 | TMPRSS2 (0.48) | TMPRSS2MARS1RIPK1POLRMT | |
| SCHEMBL26148556 | 0.89 | TMPRSS2 (0.39) | TMPRSS2MARS1SLC15A1 | |
| SCHEMBL24312592 | 0.88 | TMPRSS2 (0.46) | TMPRSS2RIPK1POLRMT | |
| SCHEMBL25381315 | 0.87 | TMPRSS2 (0.46) | TMPRSS2RIPK1POLRMT | |
| SCHEMBL24418858 | 0.87 | TMPRSS2 (0.48) | TMPRSS2MARS1RIPK1POLRMT | |
| SCHEMBL24606263 | 0.87 | TMPRSS2 (0.48) | TMPRSS2MARS1RIPK1POLRMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240317754-A1 | METHODS AND MODIFIED NUCLEOSIDES FOR TREATING CORONAVIRUS INFECTIONS | SOUTHERN UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2024-09-26 | — | — | US | disclosed |
| WO-2022142477-A1 | METHODS AND MODIFIED NUCLEOSIDES FOR TREATING CORONAVIRUS INFECTIONS | SOUTHERN UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2022-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240317754-A1 | METHODS AND MODIFIED NUCLEOSIDES FOR TREATING CORONAVIRUS INFECTIONS | PNP, MTAP, NSUN2 | TMPRSS2 69/4885MARS1 794/4885TRPM2 3188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.