Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.45 |
| ▸ | IARS1 | P41252 | 8/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24606265 | 1.00 | TMPRSS2 (0.45) | TMPRSS2IARS1RIPK1 | |
| SCHEMBL24312544 | 0.93 | TMPRSS2 (0.47) | TMPRSS2RIPK1 | |
| SCHEMBL23959956 | 0.93 | TMPRSS2 (0.47) | TMPRSS2RIPK1 | |
| SCHEMBL24606264 | 0.91 | TMPRSS2 (0.48) | TMPRSS2RIPK1 | |
| SCHEMBL24418858 | 0.91 | TMPRSS2 (0.48) | TMPRSS2RIPK1 | |
| SCHEMBL24606263 | 0.91 | TMPRSS2 (0.48) | TMPRSS2RIPK1 | |
| SCHEMBL23960045 | 0.90 | TMPRSS2 (0.48) | TMPRSS2RIPK1 | |
| Obeldesivir SCHEMBL23959875 | 0.90 | TMPRSS2 (0.49) | TMPRSS2RIPK1 | |
| Obeldesivir SCHEMBL27216326 | 0.90 | TMPRSS2 (0.49) | TMPRSS2RIPK1 | |
| SCHEMBL25821935 | 0.88 | TMPRSS2 (0.48) | TMPRSS2RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240317754-A1 | METHODS AND MODIFIED NUCLEOSIDES FOR TREATING CORONAVIRUS INFECTIONS | SOUTHERN UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2024-09-26 | — | — | US | disclosed |
| WO-2022142477-A1 | METHODS AND MODIFIED NUCLEOSIDES FOR TREATING CORONAVIRUS INFECTIONS | SOUTHERN UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2022-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240317754-A1 | METHODS AND MODIFIED NUCLEOSIDES FOR TREATING CORONAVIRUS INFECTIONS | PNP, MTAP, NSUN2 | TMPRSS2 69/4885IARS1 1297/4885RIPK1 3158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.