Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | DAO | P14920 | 3/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29751529 | 1.00 | CSNK2A2 (0.46) | CSNK2A2CSNK2BCSNK2A1LMNADAO | |
| SCHEMBL22972503 | 0.81 | PDE3B (0.49) | CSNK2A2CSNK2BCSNK2A1LMNADAO | |
| SCHEMBL29751458 | 0.81 | DAO (0.47) | CSNK2A2CSNK2BCSNK2A1LMNADAO | |
| SCHEMBL24058145 | 0.81 | DAO (0.47) | CSNK2A2CSNK2BCSNK2A1LMNADAO | |
| SCHEMBL21050770 | 0.79 | PDE3B (0.43) | CSNK2A2CSNK2BCSNK2A1LMNADAO | |
| SCHEMBL23832583 | 0.78 | CSNK2A2 (0.42) | CSNK2A2CSNK2BCSNK2A1LMNAPDE3B | |
| SCHEMBL24854116 | 0.76 | LMNA (0.40) | CSNK2A2CSNK2BCSNK2A1LMNADAO | |
| SCHEMBL13015482 | 0.76 | PDE3B (0.40) | LMNADAOPDE3BPDE3ADPP4 | |
| SCHEMBL24854272 | 0.76 | LMNA (0.40) | CSNK2A2CSNK2BCSNK2A1LMNADAO | |
| SCHEMBL13015480 | 0.74 | DAO (0.66) | LMNADAOPDE3BPDE3ADPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022147465-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-07-07 | — | — | WO | disclosed |