Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25337708 | 0.87 | NPC1 (0.38) | NPC1DGAT1TSHR | |
| SCHEMBL24607484 | 0.86 | NPC1 (0.37) | NPC1DGAT1 | |
| SCHEMBL31129761 | 0.82 | NPC1 (0.38) | NPC1DGAT1TSHR | |
| SCHEMBL31276144 | 0.82 | NPC1 (0.40) | NPC1DGAT1TSHR | |
| SCHEMBL29502401 | 0.81 | NPC1 (0.41) | NPC1DGAT1TSHR | |
| SCHEMBL13015496 | 0.81 | NPC1 (0.41) | NPC1DGAT1TSHR | |
| SCHEMBL24668167 | 0.78 | NPC1 (0.42) | NPC1DGAT1TSHR | |
| SCHEMBL29729427 | 0.78 | NPC1 (0.42) | NPC1DGAT1TSHR | |
| SCHEMBL31276238 | 0.77 | NPC1 (0.43) | NPC1TSHR | |
| SCHEMBL30702016 | 0.77 | NPC1 (0.34) | NPC1DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4271664-A1 | IRAK DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2023-11-08 | — | — | EP | disclosed |
| CN-116867758-A | IRAK degradation agents and uses thereof | 凯麦拉医疗公司 | 2023-10-10 | — | — | CN | disclosed |
| WO-2022147465-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-07-07 | — | — | WO | disclosed |
| WO-2022147465-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-07-07 | — | — | WO | disclosed |