Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27191727 | 1.00 | NPC1 (0.34) | NPC1MAPTDGAT1 | |
| SCHEMBL30702002 | 0.85 | NPC1 (0.36) | NPC1MAPT | |
| SCHEMBL27191846 | 0.85 | NPC1 (0.36) | NPC1MAPT | |
| SCHEMBL13015496 | 0.82 | NPC1 (0.41) | NPC1MAPTDGAT1 | |
| SCHEMBL29502401 | 0.82 | NPC1 (0.41) | NPC1MAPTDGAT1 | |
| SCHEMBL24607455 | 0.81 | NPC1 (0.35) | NPC1DGAT1 | |
| SCHEMBL31129761 | 0.78 | NPC1 (0.38) | NPC1DGAT1 | |
| SCHEMBL31276144 | 0.78 | NPC1 (0.40) | NPC1MAPTDGAT1 | |
| SCHEMBL24607798 | 0.77 | NPC1 (0.38) | NPC1DGAT1 | |
| SCHEMBL25337708 | 0.76 | NPC1 (0.38) | NPC1DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565574-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2025-06-11 | — | — | EP | disclosed |
| CN-119731159-A | SARS-CoV2 main proteinase inhibitor | 吉利德科学公司 | 2025-03-28 | — | — | CN | disclosed |
| WO-2024031089-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-02-08 | — | — | WO | disclosed |