Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 17/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 17/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29751074 | 1.00 | DDB1 (0.49) | DDB1CRBNBRD4PDK4NAMPT | |
| SCHEMBL22836102 | 0.92 | DDB1 (0.48) | DDB1CRBNBRD4PDK4NAMPT | |
| SCHEMBL31160909 | 0.92 | DDB1 (0.48) | DDB1CRBNBRD4PDK4NAMPT | |
| SCHEMBL26101530 | 0.92 | DDB1 (0.48) | DDB1CRBN | |
| SCHEMBL25036239 | 0.85 | DDB1 (0.46) | DDB1CRBN | |
| SCHEMBL26101360 | 0.85 | DDB1 (0.45) | DDB1CRBNBRD4 | |
| SCHEMBL25036954 | 0.84 | BRD4 (0.43) | DDB1CRBNBRD4PDK4NAMPT | |
| SCHEMBL25036968 | 0.83 | DDB1 (0.45) | DDB1CRBNBRD4PDK4NAMPT | |
| SCHEMBL30273817 | 0.83 | DDB1 (0.45) | DDB1CRBNBRD4PDK4NAMPT | |
| SCHEMBL30273425 | 0.83 | DDB1 (0.45) | DDB1CRBNBRD4PDK4NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250051338-A1 | TYK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2025-02-13 | — | — | US | disclosed |
| WO-2023076161-A1 | TYK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-05-04 | — | — | WO | disclosed |
| WO-2023076161-A1 | TYK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-05-04 | — | — | WO | disclosed |
| WO-2022147465-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250051338-A1 | TYK2 DEGRADERS AND USES THEREOF | TYK2, DYRK2, DYRK1A | DDB1 2403/4885CRBN 111/4885BRD4 286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.