Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 12/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 12/20 | 0.45 |
| ▸ | CDK7 | P50613 | 1/20 | 0.42 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.42 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30273817 | 1.00 | DDB1 (0.45) | DDB1CRBNCDK7CDK13CDK12 | |
| SCHEMBL22836102 | 0.91 | DDB1 (0.48) | DDB1CRBNCDK7CDK13CDK12 | |
| SCHEMBL31160909 | 0.91 | DDB1 (0.48) | DDB1CRBNCDK7CDK13CDK12 | |
| SCHEMBL30273425 | 0.90 | DDB1 (0.45) | DDB1CRBNCDK7CDK13CDK12 | |
| SCHEMBL23541145 | 0.89 | CDK7 (0.44) | DDB1CRBNCDK7CDK13CDK12 | |
| SCHEMBL25036367 | 0.89 | DDB1 (0.44) | DDB1CRBNCDK7CDK13CDK12 | |
| SCHEMBL30273873 | 0.89 | DDB1 (0.44) | DDB1CRBNCDK7CDK13CDK12 | |
| SCHEMBL30274020 | 0.87 | DDB1 (0.42) | DDB1CRBNCDK7CDK13CDK12 | |
| SCHEMBL30273802 | 0.86 | DDB1 (0.46) | DDB1CRBNCDK7CDK13CDK12 | |
| SCHEMBL23541275 | 0.84 | DDB1 (0.45) | DDB1CRBNCDK7CDK13CDK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023019166-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | CALICO LIFE SCIENCES LLC (US) | 2023-02-16 | — | — | WO | disclosed |