SCHEMBL24609396

SCHEMBL24609396

c1ccc(-c2ccccc2-n2c3ccccc3c3cc4c5ccccc5n(-c5ccc(-c6cccc7ccccc67)cc5)c4cc32)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.42
ATM Q13315 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA9 Q16790 2/20 0.39
PDE6D O43924 1/20 0.36
MCL1 Q07820 1/20 0.36
ACMSD Q8TDX5 1/20 0.36
ALDH1A1 P00352 2/20 0.35
TNF P01375 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
MAPK14 Q16539 1/20 0.35
PPARG P37231 3/20 0.34
PPARA Q07869 3/20 0.34
CYP2C9 P11712 2/20 0.34
CYP2C19 P33261 2/20 0.34
PPARD Q03181 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23233773 0.93 KDM4E (0.46) KDM4EATML3MBTL1CA12CA1
SCHEMBL23119098 0.92 KDM4E (0.42) KDM4EATML3MBTL1CA12CA1
SCHEMBL23118789 0.92 KDM4E (0.42) KDM4EATML3MBTL1CA12CA1
SCHEMBL24404272 0.92 KDM4E (0.36) KDM4EATML3MBTL1CA12CA1
SCHEMBL17019432 0.92 KDM4E (0.51) KDM4EATML3MBTL1CA12CA1
SCHEMBL22174283 0.92 KDM4E (0.46) KDM4EATML3MBTL1CA12CA1
SCHEMBL23119072 0.91 KDM4E (0.40) KDM4EATML3MBTL1CA12CA1
SCHEMBL23119002 0.91 KDM4E (0.40) KDM4EATML3MBTL1CA12CA1
SCHEMBL24404259 0.91 PDE6D (0.36) KDM4EATML3MBTL1CA12CA1
SCHEMBL24678344 0.91 L3MBTL1 (0.49) KDM4EATML3MBTL1PDE6DALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022146012-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE 삼성에스디아이 주식회사 2022-07-07 WO disclosed