Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.33 |
| ▸ | MMP9 | P14780 | 3/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 10/20 | 0.33 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.33 |
| ▸ | CCKAR | P32238 | 1/20 | 0.31 |
| ▸ | CCKBR | P32239 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12175972 | 0.90 | PTPN1 (0.36) | PTPN1PTPN22CXCR3 | |
| SCHEMBL15986399 | 0.90 | PTPN1 (0.36) | PTPN1PTPN22CXCR3 | |
| SCHEMBL14353449 | 0.88 | PTPN1 (0.37) | MMP2MMP9PTPN1PTPN22AKT1 | |
| SCHEMBL14353446 | 0.88 | PTPN1 (0.37) | MMP2MMP9PTPN1PTPN22AKT1 | |
| SCHEMBL12175886 | 0.88 | SCN9A (0.36) | PTPN1PTPN22AKT1 | |
| SCHEMBL2584858 | 0.86 | PTPN1 (0.33) | MMP2MMP9PTPN1PTPN22AKT1 | |
| SCHEMBL2584855 | 0.86 | PTPN1 (0.33) | MMP2MMP9PTPN1PTPN22AKT1 | |
| SCHEMBL14479942 | 0.83 | CCKBR (0.36) | PTPN1PTPN22CCKBRAKT1 | |
| SCHEMBL2488543 | 0.81 | SUCNR1 (0.36) | — | |
| SCHEMBL14353494 | 0.80 | CHRM1 (0.37) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE45108-E1 | Quinolone compound and pharmaceutical composition | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2014-09-02 | — | — | US | disclosed |
| EP-2364298-A1 | Quinolone compound and pharmaceutical composition | Otsuka Pharmaceutical Co., Ltd. (JP) | 2011-09-14 | — | — | EP | disclosed |
| WO-2010064735-A1 | QUINOLONE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-06-10 | — | — | WO | disclosed |