SCHEMBL2461053

SCHEMBL2461053

C=Cc1ccccc1[P+](Cc1ccccc1)(c1ccccc1)c1ccccc1.Cc1ccc(S(=O)(=O)[O-])cc1

nearest known ligand 0.38

Known targets — ChEMBL curated mechanism

CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 3/20 0.38
CYP3A4 P08684 3/20 0.36
CYP1A2 P05177 2/20 0.36
BCHE P06276 1/20 0.36
ACHE P22303 1/20 0.36
CA12 O43570 1/20 0.36
ATM Q13315 1/20 0.36
CA9 Q16790 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
MCHR1 Q99705 1/20 0.35
ALDH1A1 P00352 2/20 0.35
GAA P10253 1/20 0.35
CYP2C9 P11712 2/20 0.34
CYP2C19 P33261 2/20 0.34
LMNA P02545 3/20 0.34
MAPT P10636 1/20 0.34
C5AR1 P21730 1/20 0.34
CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL30240044 0.88 SNCA (0.36) CYP1A2
Sulfuric Acid SCHEMBL30070980 0.85 SNCA (0.38) CYP1A2ALDH1A1CYP2C19CYP2D6
SCHEMBL9633460 0.85 POLB (0.34) LMNA
SCHEMBL4921374 0.84 CYP3A4 (0.46) CNR2CYP3A4CYP1A2BCHEACHE
SCHEMBL2461048 0.82 CYP3A4 (0.40) CNR2CYP3A4CYP1A2BCHEACHE
Formic Acid SCHEMBL30601055 0.81 SNCA (0.37) CYP1A2ALDH1A1CYP2C19LMNACYP2D6
Hydrochloric Acid SCHEMBL10486017 0.81 SNCA (0.41) CYP1A2ALDH1A1CYP2C19CYP2D6
Acetic Acid SCHEMBL28850582 0.80 SNCA (0.38) CYP1A2ALDH1A1CYP2C19LMNACYP2D6
Sulfurous Acid SCHEMBL28174995 0.78 SNCA (0.38) CYP1A2ALDH1A1CYP2C19CYP2D6
SCHEMBL9703420 0.76 C5AR1 (0.43) CNR2CYP3A4CYP1A2BCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1352756-B1 Ink recording element containing stabilized polymeric particles EASTMAN KODAK CO (US) 2011-09-21 EP disclosed
EP-1321302-B1 inkjet recording element with porous organic particles EASTMAN KODAK CO (US) 2009-08-05 EP disclosed
US-7390844-B2 Polymer particle stabilized by dispersant and method of preparation EASTMAN KODAK COMPANY (US) 2008-06-24 US disclosed
EP-1245401-B1 Ink jet recording element and printing method EASTMAN KODAK CO (US) 2007-11-28 EP disclosed
US-7059714-B2 Ink printing method utilizing stabilized polymeric particles EASTMAN KODAK COMPANY (US) 2006-06-13 US disclosed
US-20050159507-A1 Polymer particle stabilized by dispersant and method of preparation BANK OF AMERICA, N.A., AS AGENT 2005-07-21 US disclosed
US-6906157-B2 Polymer particle stabilized by dispersant and method of preparation EASTMAN KODAK COMPANY (US) 2005-06-14 US disclosed
US-6866902-B2 Ink recording element containing stabilized polymeric particles EASTMAN KODAK COMPANY (US) 2005-03-15 US disclosed
US-20030197773-A1 Ink printing method utilizing stabilized polymeric particles EASTMAN KODAK COMPANY 2003-10-23 US disclosed
US-20030198761-A1 Ink recording element containing stabilized polymeric particles EASTMAN KODAK COMPANY 2003-10-23 US disclosed
EP-1352919-A1 Polymer particle stabilized by dispersant and method of preparation EASTMAN KODAK COMPANY (US) 2003-10-15 EP disclosed
EP-1352755-A2 Ink printing method utilizing stabilized polymeric particles EASTMAN KODAK COMPANY (US) 2003-10-15 EP disclosed
US-20030148073-A1 Porous organic particles for ink recording element use EASTMAN KODAK COMPANY 2003-08-07 US disclosed
EP-1321302-A2 Porous organic particles for ink recording element use EASTMAN KODAK COMPANY (US) 2003-06-25 EP disclosed
US-6554419-B2 Loading a printer that is responsive to digital data signals with recording element of a support having an image-receiving layer made of porous polymeric particles in a polymeric binder EASTMAN KODAK COMPANY 2003-04-29 US disclosed
US-6541103-B2 Support with an image-receiving layer of porous polymers of ethylenically unsaturated and cationic group containing monomers EASTMAN KODAK COMPANY 2003-04-01 US disclosed
US-20030044581-A1 Ink jet recording element EASTMAN KODAK COMPANY 2003-03-06 US disclosed
US-20020176966-A1 Ink jet printing method EASTMAN KODAK COMPANY 2002-11-28 US disclosed
EP-1245401-A2 Ink jet recording element and printing method EASTMAN KODAK COMPANY (US) 2002-10-02 EP disclosed
US-5021473-A With mixture of polymer(s) and catonic compound HOECHST AKTIENGESELLSCHAFT (DE) 1991-06-04 US disclosed