Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9634534 | 0.83 | HIF1A (0.52) | CYP3A4CYP2D6LMNAMAPK1THPO | |
| SCHEMBL6230992 | 0.81 | CYP3A4 (0.46) | CNR2CYP3A4CYP2D6LMNAMAPK1 | |
| SCHEMBL4921374 | 0.79 | CYP3A4 (0.46) | CNR2CYP3A4CYP2D6LMNAMAPK1 | |
| SCHEMBL2461048 | 0.79 | CYP3A4 (0.40) | C5AR1CNR2CYP3A4CYP2D6LMNA | |
| Tetraphenylphosphonium SCHEMBL28641132 | 0.77 | CA12 (0.46) | C5AR1CYP3A4CYP2D6LMNAMAPK1 | |
| Butyltriphenylphosphonium SCHEMBL6928248 | 0.77 | CNR2 (0.45) | CNR2CYP3A4CYP2D6LMNAMAPK1 | |
| SCHEMBL9634538 | 0.77 | ALDH1A1 (0.51) | CNR2CYP3A4CYP2D6LMNAMAPK1 | |
| SCHEMBL128521 | 0.76 | CA12 (0.44) | C5AR1CNR2CYP3A4CYP2D6LMNA | |
| SCHEMBL6232589 | 0.75 | ALDH1A1 (0.40) | CYP3A4CYP2D6LMNAMAPK1THPO | |
| SCHEMBL9777641 | 0.75 | CYP3A4 (0.41) | CNR2CYP3A4CYP2D6LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147747-A | Low fusing temperature tone powder of crosslinked crystalline and amorphous polyesters | EASTMAN KODAK COMPANY (US) | 1992-09-15 | — | — | US | disclosed |