Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 20/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24610985 | 0.88 | OPRK1 (0.51) | OPRK1OPRM1 | |
| SCHEMBL20670802 | 0.88 | OPRK1 (0.50) | OPRK1OPRM1 | |
| SCHEMBL20670934 | 0.88 | OPRK1 (0.61) | OPRK1OPRM1 | |
| SCHEMBL20670665 | 0.87 | OPRK1 (0.67) | OPRK1OPRM1 | |
| SCHEMBL20670668 | 0.87 | OPRK1 (0.49) | OPRK1OPRM1 | |
| SCHEMBL20670864 | 0.87 | OPRK1 (0.62) | OPRK1OPRM1 | |
| SCHEMBL20499953 | 0.86 | OPRK1 (0.51) | OPRK1OPRM1 | |
| SCHEMBL20670804 | 0.86 | OPRK1 (0.51) | OPRK1OPRM1 | |
| SCHEMBL20499931 | 0.84 | OPRK1 (0.66) | OPRK1OPRM1 | |
| SCHEMBL24610982 | 0.82 | OPRK1 (0.50) | OPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3596069-B1 | KAPPA OPIOID RECEPTOR ANTAGONISTS AND PRODUCTS AND METHODS RELATED THERETO | SCRIPPS RESEARCH INST (US) | 2022-07-13 | — | — | EP | disclosed |