Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20442588 | 0.86 | ESR1 (0.58) | ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL7709195 | 0.83 | ESR1 (0.66) | ESR1ESR2 | |
| SCHEMBL20442587 | 0.83 | ESR1 (0.54) | ESR1ESR2 | |
| SCHEMBL7454293 | 0.82 | ESR1 (0.63) | ESR1ESR2 | |
| SCHEMBL15661595 | 0.81 | ESR1 (1.00) | ESR1ESR2 | |
| SCHEMBL20442662 | 0.81 | ESR1 (0.69) | ESR1ESR2 | |
| SCHEMBL25079389 | 0.81 | ESR1 (0.80) | ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL8159432 | 0.79 | ESR1 (0.62) | ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL7918788 | 0.79 | ESR1 (0.62) | ESR1ESR2 | |
| SCHEMBL24654407 | 0.78 | ESR1 (0.98) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11384063-B2 | Modulators of estrogen receptor proteolysis and associated methods of use | ARVINAS OPERATIONS, INC. (US) | 2022-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11384063-B2 | Modulators of estrogen receptor proteolysis and associated methods of use | ADRM1, MDM2, ESR2 | ESR1 15/4885ESR2 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.