Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.43 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19607724 | 0.99 | KMT2A (0.50) | KMT2ARXFP1LMNAADORA2BTRPA1 | |
| SCHEMBL18256065 | 0.81 | KMT2A (0.64) | KMT2ARXFP1LMNAADORA2BMAPT | |
| SCHEMBL19607817 | 0.80 | KMT2A (0.46) | KMT2ARXFP1LMNAADORA2BTRPA1 | |
| SCHEMBL18256137 | 0.79 | KMT2A (0.66) | KMT2ARXFP1LMNAADORA2BMAPT | |
| SCHEMBL17682143 | 0.78 | ADORA2B (0.61) | RXFP1LMNAADORA2BPDE4ACYP1A2 | |
| SCHEMBL20182588 | 0.78 | KMT2A (0.47) | KMT2ARXFP1LMNAADORA2BTRPA1 | |
| SCHEMBL18819581 | 0.78 | KMT2A (0.50) | KMT2ARXFP1LMNAADORA2BTRPA1 | |
| SCHEMBL19607604 | 0.77 | PDE4A (0.46) | KMT2ARXFP1LMNAADORA2BTRPA1 | |
| SCHEMBL18256060 | 0.77 | KMT2A (0.66) | KMT2ARXFP1LMNAADORA2BMAPT | |
| SCHEMBL18819573 | 0.77 | KMT2A (0.47) | KMT2ARXFP1LMNAADORA2BTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49128-E1 | Hydroxyl purine compounds and applications thereof | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2022-07-12 | — | — | US | disclosed |