Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | PDE4A | P27815 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18819573 | 0.93 | KMT2A (0.47) | KMT2ARXFP1TRPA1ALDH1A1LMNA | |
| SCHEMBL17682188 | 0.89 | ADORA2B (0.47) | RXFP1LMNAPDE4ACYP1A2NFKB1 | |
| SCHEMBL30025374 | 0.89 | ADORA2B (0.47) | RXFP1LMNAPDE4ACYP1A2NFKB1 | |
| SCHEMBL30025113 | 0.89 | ADORA2B (0.47) | RXFP1LMNAPDE4ACYP1A2NFKB1 | |
| SCHEMBL17682124 | 0.89 | ADORA2B (0.47) | RXFP1LMNAPDE4ACYP1A2NFKB1 | |
| SCHEMBL19607674 | 0.89 | KMT2A (0.47) | KMT2ARXFP1TRPA1ALDH1A1LMNA | |
| SCHEMBL17682190 | 0.89 | ADORA2B (0.47) | RXFP1LMNAPDE4ACYP1A2NFKB1 | |
| SCHEMBL17682279 | 0.87 | KMT2A (0.48) | KMT2ARXFP1TRPA1ALDH1A1LMNA | |
| SCHEMBL17682249 | 0.87 | KMT2A (0.48) | KMT2ARXFP1TRPA1ALDH1A1LMNA | |
| SCHEMBL17682280 | 0.87 | KMT2A (0.48) | KMT2ARXFP1TRPA1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49128-E1 | Hydroxyl purine compounds and applications thereof | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2022-07-12 | — | — | US | disclosed |