SCHEMBL24612007

SCHEMBL24612007

O=C1Nc2ccccc2C(c2ccccc2)=NC1Nc1ncc(C2=CCCC=C2)o1

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 17/20 0.45
CCKAR P32238 12/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20098199 0.86 CCKBR (0.53) CCKBRCCKAR
SCHEMBL20098472 0.81 CCKBR (0.50) CCKBRCCKAR
SCHEMBL20098440 0.81 CCKBR (0.57) CCKBRCCKAR
SCHEMBL24612240 0.79 CCKBR (0.44) CCKBRCCKAR
SCHEMBL20098248 0.79 CCKBR (0.59) CCKBRCCKAR
SCHEMBL20098322 0.74 CCKBR (0.60) CCKBRCCKAR
SCHEMBL20098024 0.74 CCKBR (0.52) CCKBRCCKAR
SCHEMBL21755181 0.73 CCKBR (0.54) CCKBRCCKAR
SCHEMBL20098042 0.73 CCKBR (0.54) CCKBRCCKAR
SCHEMBL20098169 0.72 CCKBR (0.53) CCKBRCCKAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3324977-B1 BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS ENANTA PHARM INC (US) 2022-07-13 EP disclosed