Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 9/20 | 0.41 |
| ▸ | CCKBR | P32239 | 2/20 | 0.41 |
| ▸ | CCKAR | P32238 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | MST1 | P26927 | 1/20 | 0.36 |
| ▸ | STK4 | Q13043 | 1/20 | 0.36 |
| ▸ | STK3 | Q13188 | 1/20 | 0.36 |
| ▸ | STK26 | Q9P289 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24612393 | 0.88 | CCKAR (0.44) | CBLBCCKBRCCKARBACE1ALDH1A1 | |
| SCHEMBL24611903 | 0.77 | CBLB (0.41) | CBLBCCKBRCCKARBACE1ALDH1A1 | |
| SCHEMBL20866897 | 0.76 | CCKBR (0.49) | CBLBCCKBRCCKAR | |
| SCHEMBL20866898 | 0.76 | CCKBR (0.49) | CBLBCCKBRCCKAR | |
| SCHEMBL24612409 | 0.76 | CCKBR (0.41) | CBLBCCKBRCCKARBACE1ALDH1A1 | |
| SCHEMBL20098124 | 0.76 | CCKBR (0.44) | CBLBCCKBRCCKARLRRK2 | |
| SCHEMBL20098252 | 0.76 | CCKBR (0.44) | CBLBCCKBRCCKARLRRK2 | |
| SCHEMBL24612102 | 0.76 | CBLB (0.46) | CBLBCCKBRCCKARBACE1ALDH1A1 | |
| SCHEMBL24612057 | 0.73 | CCKBR (0.46) | CBLBCCKBRCCKARLRRK2MST1 | |
| SCHEMBL20098317 | 0.73 | CCKBR (0.46) | CBLBCCKBRCCKARLRRK2MST1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3324977-B1 | BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS | ENANTA PHARM INC (US) | 2022-07-13 | — | — | EP | disclosed |