Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 9/20 | 0.43 |
| ▸ | CCKAR | P32238 | 7/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NOTCH1 | P46531 | 3/20 | 0.36 |
| ▸ | RBPJ | Q06330 | 3/20 | 0.36 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24612409 | 0.80 | CCKBR (0.41) | CCKBRCCKARCHRM1MEN1ALDH1A1 | |
| SCHEMBL24611903 | 0.74 | CBLB (0.41) | CCKBRCCKARMEN1ALDH1A1KMT2A | |
| SCHEMBL24612022 | 0.72 | CCKBR (0.45) | CCKBRCCKARCHRM1MEN1ALDH1A1 | |
| SCHEMBL24612393 | 0.70 | CCKAR (0.44) | CCKBRCCKARMEN1ALDH1A1KMT2A | |
| SCHEMBL24612375 | 0.69 | CCKBR (0.51) | CCKBRCCKARCHRM1MEN1ALDH1A1 | |
| SCHEMBL20098621 | 0.68 | CCKBR (0.47) | CCKBRCCKARNOTCH1RBPJ | |
| SCHEMBL20867311 | 0.67 | CCKBR (0.50) | CCKBRCCKARNOTCH1RBPJ | |
| SCHEMBL24611848 | 0.67 | CCKBR (0.48) | CCKBRCCKARCHRM1MEN1ALDH1A1 | |
| SCHEMBL24611851 | 0.67 | CCKBR (0.53) | CCKBRCCKARCHRM1MEN1ALDH1A1 | |
| SCHEMBL22440664 | 0.66 | CCKBR (0.49) | CCKBRCCKARMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3324977-B1 | BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS | ENANTA PHARM INC (US) | 2022-07-13 | — | — | EP | disclosed |