Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKAR | P32238 | 10/20 | 0.43 |
| ▸ | CCKBR | P32239 | 9/20 | 0.43 |
| ▸ | NOTCH1 | P46531 | 4/20 | 0.39 |
| ▸ | NOTCH3 | Q9UM47 | 3/20 | 0.39 |
| ▸ | CBLB | Q13191 | 4/20 | 0.38 |
| ▸ | RBPJ | Q06330 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24612173 | 0.85 | CCKBR (0.46) | CCKARCCKBRCBLB | |
| SCHEMBL24611975 | 0.79 | CCKAR (0.45) | CCKARCCKBRNOTCH1NOTCH3CBLB | |
| SCHEMBL20867039 | 0.78 | CCKAR (0.45) | CCKARCCKBRNOTCH1NOTCH3CBLB | |
| SCHEMBL20866968 | 0.74 | CCKBR (0.58) | CCKARCCKBR | |
| SCHEMBL20866699 | 0.73 | CCKBR (0.61) | CCKARCCKBRNOTCH1RBPJ | |
| SCHEMBL24612045 | 0.72 | CCKBR (0.74) | CCKARCCKBR | |
| SCHEMBL20866649 | 0.72 | CCKBR (0.74) | CCKARCCKBR | |
| SCHEMBL20867015 | 0.72 | CCKBR (0.58) | CCKARCCKBR | |
| SCHEMBL24612185 | 0.72 | CCKBR (0.47) | CCKARCCKBRCBLB | |
| SCHEMBL20866819 | 0.71 | CCKBR (0.63) | CCKARCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3324977-B1 | BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS | ENANTA PHARM INC (US) | 2022-07-13 | — | — | EP | disclosed |