SCHEMBL24612499

SCHEMBL24612499

CCn1nc(C(=O)NCC2(O)CCC(C)CC2)c(C)c1-c1cnc(CC(C)(C)C(F)(F)F)cc1C(F)F

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ RORC P51449 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23478185 0.92 RORC (0.84) RORC
SCHEMBL21605586 0.92 RORC (0.84) RORC
SCHEMBL23504311 0.92 RORC (0.84) RORC
SCHEMBL24612486 0.89 RORC (1.00) RORC
SCHEMBL21605674 0.85 RORC (0.85) RORC
SCHEMBL23504307 0.85 RORC (0.85) RORC
SCHEMBL23478271 0.85 RORC (0.85) RORC
SCHEMBL23478257 0.81 RORC (0.85) RORC
SCHEMBL21605677 0.81 RORC (0.85) RORC
SCHEMBL24612463 0.81 RORC (0.77) RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3807261-B1 PYRIDINYL PYRAZOLES AS MODULATORS OF RORYT JANSSEN PHARMACEUTICA NV (BE) 2022-07-13 — — EP disclosed
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