SCHEMBL2461328

SCHEMBL2461328

O=[N+]([O-])C[C@@H](O)c1ccc(Br)cc1

nearest known ligand 0.68

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.68
IGF1R P08069 4/20 0.46
KDM4E B2RXH2 3/20 0.42
MEN1 O00255 3/20 0.42
MAPT P10636 3/20 0.42
KMT2A Q03164 3/20 0.42
LMNA P02545 2/20 0.42
ATM Q13315 1/20 0.42
APAF1 O14727 1/20 0.40
HSP90AA1 P07900 1/20 0.40
GAA P10253 1/20 0.40
HPGD P15428 1/20 0.40
NPC1 O15118 1/20 0.38
HMOX1 P09601 1/20 0.36
CYP1A2 P05177 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2461281 1.00 ALDH1A1 (0.68) ALDH1A1IGF1RKDM4EMEN1MAPT
SCHEMBL28055414 1.00 ALDH1A1 (0.68) ALDH1A1IGF1RKDM4EMEN1MAPT
SCHEMBL27807831 0.82 ALDH1A1 (0.70) ALDH1A1KDM4EMEN1MAPTKMT2A
SCHEMBL27807830 0.82 ALDH1A1 (0.70) ALDH1A1KDM4EMEN1MAPTKMT2A
SCHEMBL23549438 0.81 ALDH1A1 (0.53) ALDH1A1IGF1RKDM4EMEN1MAPT
SCHEMBL531072 0.81 ALDH1A1 (0.68) ALDH1A1KDM4EMEN1MAPTKMT2A
SCHEMBL4242515 0.81 ALDH1A1 (1.00) ALDH1A1IGF1RKDM4EMEN1MAPT
SCHEMBL6782597 0.81 ALDH1A1 (0.68) ALDH1A1KDM4EMEN1MAPTKMT2A
SCHEMBL28826475 0.81 ALDH1A1 (1.00) ALDH1A1IGF1RKDM4EMEN1MAPT
SCHEMBL28826474 0.81 ALDH1A1 (0.68) ALDH1A1KDM4EMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102892505-B Chiral heterogeneous catalyst for asymmetric nitroaldol reaction COUNCIL SCIENT IND RES 2015-02-11 CN disclosed
US-8557726-B2 Chiral heterogeneous catalyst for assymmetric nitroaldol reaction COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2013-10-15 US disclosed
US-20130096333-A1 Chiral Heterogeneous Catalyst for Assymmetric Nitroaldol Reaction COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2013-04-18 US disclosed
CN-102892505-A Chiral heterogeneous catalyst for asymmetric nitroaldol reaction COUNCIL SCIENT IND RES 2013-01-23 CN disclosed
EP-2544818-A1 CHIRAL HETEROGENEOUS CATALYST FOR ASYMMETRIC NITROALDOL REACTION Council of Scientific & Industrial Research (IN) 2013-01-16 EP disclosed
CN-101830919-B Zinc nitride and copper nitride compound of chiral alpha-phenylethylamine and use thereof UNIV HEFEI TECHNOLOGY 2012-06-20 CN disclosed
WO-2011110895-A1 CHIRAL HETEROGENEOUS CATALYST FOR ASYMMETRIC NITROALDOL REACTION COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2011-09-15 WO disclosed
CN-101830919-A Zinc nitride and copper nitride compound of chiral alpha-phenylethylamine and use thereof UNIV HEFEI TECHNOLOGY 2010-09-15 CN disclosed