Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | PPIB | P23284 | 1/20 | 0.43 |
| ▸ | PPIA | P62937 | 1/20 | 0.43 |
| ▸ | PPID | Q08752 | 1/20 | 0.43 |
| ▸ | PPIG | Q13427 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13199136 | 0.91 | TSHR (0.49) | LMNACYP1A2CYP3A4TSHRACSS2 | |
| SCHEMBL13199166 | 0.86 | TSHR (0.46) | LMNATSHRACSS2HTTMAPT | |
| SCHEMBL17583195 | 0.86 | NPSR1 (0.51) | CYP1A2TSHRCYP2C9CYP2C19ACSS2 | |
| SCHEMBL5003336 | 0.86 | NPSR1 (0.47) | LMNATSHRACSS2HTTMAPT | |
| SCHEMBL31306426 | 0.84 | CA12 (0.55) | TSHRACSS2HTTALDH1A1MAPT | |
| SCHEMBL2396473 | 0.84 | MAPT (0.50) | LMNACYP1A2TSHRCYP2C9CYP2C19 | |
| SCHEMBL17420736 | 0.83 | LMNA (0.48) | LMNACYP1A2CYP3A4TSHRCYP2C9 | |
| SCHEMBL28452636 | 0.83 | HDAC6 (0.42) | LMNATSHRACSS2HTTNPSR1 | |
| SCHEMBL1172128 | 0.83 | NPSR1 (0.48) | LMNACYP1A2TSHRCYP2C9CYP2C19 | |
| SCHEMBL2879531 | 0.83 | CA1 (0.58) | LMNACYP1A2CYP3A4MAOATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022148196-A1 | MULTIKINASE INHIBITOR AND USE THEREOF | 苏州安睿药业有限公司 | 2022-07-14 | — | — | WO | disclosed |