Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24615831 | 0.79 | SMN1; SMN2 (0.45) | SMN1; SMN2PIK3CD | |
| SCHEMBL24811738 | 0.79 | SMN1; SMN2 (0.45) | SMN1; SMN2PIK3CD | |
| SCHEMBL20148575 | 0.75 | SMN1; SMN2 (0.45) | SMN1; SMN2PIK3CD | |
| SCHEMBL20715276 | 0.74 | CYP2D6 (0.33) | — | |
| SCHEMBL21482317 | 0.72 | — | — | |
| SCHEMBL20738498 | 0.71 | SMN1; SMN2 (0.50) | SMN1; SMN2PIK3CD | |
| SCHEMBL26620413 | 0.71 | SMN1; SMN2 (0.50) | SMN1; SMN2PIK3CD | |
| SCHEMBL21937606 | 0.71 | SMN1; SMN2 (0.45) | SMN1; SMN2PIK3CD | |
| SCHEMBL20153143 | 0.68 | SMN1; SMN2 (0.47) | SMN1; SMN2PIK3CD | |
| SCHEMBL16866823 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022148422-A1 | BRIDGED COMPOUNDS AS KRAS G12D INHIBITOR AND DEGRADER AND THE USE THEREOF | BEIGENE, LTD. (KY) | 2022-07-14 | — | — | WO | disclosed |