Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19155593 | 0.78 | TDP1 (0.31) | KMT2AMAPTSMN1; SMN2SLC6A3MEN1 | |
| SCHEMBL12355077 | 0.77 | KMT2A (0.61) | LMNAMETAP2METAP1HDAC6KMT2A | |
| SCHEMBL19650346 | 0.76 | POLB (0.30) | TDP1ATMPOLB | |
| SCHEMBL21921326 | 0.75 | ELANE (0.39) | MAPTHSD17B10GAAALOX15TDP1 | |
| SCHEMBL20646376 | 0.73 | KMT2A (0.44) | LMNAMETAP2METAP1HDAC6KMT2A | |
| SCHEMBL20922636 | 0.73 | MAPT (0.43) | LMNAMAPTSMN1; SMN2HSD17B10TDP1 | |
| SCHEMBL19642801 | 0.73 | LMNA (0.54) | LMNAMETAP2METAP1HDAC6KMT2A | |
| SCHEMBL17502636 | 0.72 | ESR1 (0.56) | LMNAMETAP2METAP1HDAC6KMT2A | |
| SCHEMBL19642843 | 0.70 | LMNA (0.54) | LMNAMETAP2METAP1HDAC6KMT2A | |
| SCHEMBL19420680 | 0.70 | AKT1 (0.46) | LMNAMAPTSMN1; SMN2HSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220220060-A1 | CATALYST COMPOSITION FOR POLYOLEFIN POLYMERS | W.R. GRACE & CO.-CONN (US) | 2022-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220220060-A1 | CATALYST COMPOSITION FOR POLYOLEFIN POLYMERS | DNTT, TKT, APRT | LMNA 2885/4885METAP2 648/4885METAP1 602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.