Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.36 |
| ▸ | CNR1 | P21554 | 9/20 | 0.36 |
| ▸ | FAAH | O00519 | 3/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.33 |
| ▸ | ABHD12 | Q8N2K0 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24617077 | 1.00 | CNR2 (0.36) | CNR2CNR1FAAHMAP4K4BRD4 | |
| SCHEMBL29778590 | 1.00 | CNR2 (0.36) | CNR2CNR1FAAHMAP4K4BRD4 | |
| SCHEMBL24617066 | 0.93 | CNR2 (0.39) | CNR2CNR1FAAHBRD4ABHD12 | |
| SCHEMBL29778574 | 0.93 | CNR2 (0.39) | CNR2CNR1FAAHBRD4ABHD12 | |
| SCHEMBL24617093 | 0.93 | CNR2 (0.39) | CNR2CNR1FAAHBRD4ABHD12 | |
| SCHEMBL30656510 | 0.90 | GABRA5 (0.39) | CNR2CNR1FAAHBRD4 | |
| SCHEMBL24617084 | 0.90 | GABRA5 (0.39) | CNR2CNR1FAAHBRD4 | |
| SCHEMBL29778580 | 0.90 | DYRK1A (0.39) | CNR2CNR1FAAHBRD4ABHD12 | |
| SCHEMBL24617384 | 0.90 | DYRK1A (0.39) | CNR2CNR1FAAHBRD4ABHD12 | |
| SCHEMBL24617259 | 0.89 | MEN1 (0.39) | CNR2CNR1MAP4K4BRD4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022150381-A1 | SELECTIVE INHIBITORS OF ROCK1 AND ROCK2 PROTEIN KINASES AND USES THEREOF | Genosco Inc. (US) | 2022-07-14 | — | — | WO | disclosed |