⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10787062 | 0.80 | MEN1 (0.37) | — | |
| SCHEMBL25233759 | 0.78 | MEN1 (0.41) | — | |
| SCHEMBL226325 | 0.74 | — | — | |
| SCHEMBL20860351 | 0.74 | — | — | |
| SCHEMBL3332078 | 0.74 | — | — | |
| SCHEMBL24521730 | 0.74 | — | — | |
| SCHEMBL21184090 | 0.74 | — | — | |
| SCHEMBL23839182 | 0.74 | — | — | |
| SCHEMBL22958273 | 0.74 | — | — | |
| SCHEMBL20860322 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 399 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240207253-A1 | Inhibitors of CDR1 for Reversal of Azole Drug Resistance in Fungal Infections | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS | 2024-06-27 | — | — | US | claimed |
| WO-2022245951-A1 | INHIBITORS OF CDR1 FOR REVERSAL OF AZOLE DRUG RESISTANCE IN FUNGAL INFECTIONS | UNM RAINFOREST INNOVATIONS (US) | 2022-11-24 | — | — | WO | claimed |
| CN-108026372-B | Modified filler particles and silicone compositions containing the same | 莫门蒂夫性能材料有限公司 | 2022-03-15 | — | — | CN | claimed |
| US-20180208718-A1 | MODIFIED FILLER PARTICLES AND SILICONE COMPOSITIONS COMPRISING THE SAME | MOMENTIVE PERFORMANCE MATERIALS INC. | 2018-07-26 | — | — | US | claimed |
| EP-3325557-A1 | MODIFIED FILLER PARTICLES AND SILICONE COMPOSITIONS COMPRISING THE SAME | Momentive Performance Materials GmbH (DE) | 2018-05-30 | — | — | EP | claimed |
| WO-2017012715-A1 | MODIFIED FILLER PARTICLES AND SILICONE COMPOSITIONS COMPRISING THE SAME | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2017-01-26 | — | — | WO | claimed |
| CN-101910345-A | Pressure-sensitive adhesive compositions, polarizers and liquid crystal displays comprising the same | LG CHEMICAL LTD | 2010-12-08 | — | — | CN | claimed |
| US-7662849-B2 | Amidino compounds as cysteine protease inhibitors | VIROBAY, INC. (US) | 2010-02-16 | — | — | US | claimed |
| WO-2009131692-A1 | SUBSTRATES FOR DELIVERY OF PHYSIOLOGICALLY ACTIVE AGENTS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2009-10-29 | — | — | WO | claimed |
| US-20060264464-A1 | Amidino compounds as cysteine protease inhibitors | QUEST DIAGNOSTICS INVESTMENTS LLC | 2006-11-23 | — | — | US | claimed |
| US-5618826-A | Anticholinergic compounds, compositions and methods of treatment | UNIVERSITY OF FLORIDA (US) | 1997-04-08 | — | — | US | claimed |
| US-5610188-A | MYDRIATICS, ANTIPERSPIRANTS | UNIVERSITY OF FLORIDA (US) | 1997-03-11 | — | — | US | claimed |
| US-5418244-A | Antiperspirants, mydriatic | UNIVERSITY OF FLORIDA (US) | 1995-05-23 | — | — | US | claimed |
| US-5334601-A | Soft β-adrenergic blocking agents | IVAX International GmbH (CH) | 1994-08-02 | — | — | US | claimed |
| US-5258388-A | Antisecretory agents, mydriatic agents and antiperspirants | UNIVERSITY OF FLORIDA (US) | 1993-11-02 | — | — | US | claimed |
| US-5223528-A | Antisecretory agents, mydriatics, antiperspirants | UNIVERSITY OF FLORIDA (US) | 1993-06-29 | — | — | US | claimed |
| EP-0174956-B1 | SOFT $g(b)-ADRENERGIC BLOCKING AGENTS | BODOR, Nicholas S. (US) | 1990-08-16 | — | — | EP | claimed |
| US-4829086-A | Soft β-adrenergic blocking agents | IVAX International GmbH (CH) | 1989-05-09 | — | — | US | claimed |
| EP-0174956-A1 | SOFT -g(b)-ADRENERGIC BLOCKING AGENTS. | BODOR NICHOLAS S | 1986-03-26 | — | — | EP | claimed |
| WO-1985004168-A1 | SOFT beta-ADRENERGIC BLOCKING AGENTS | BODOR NICHOLAS S | 1985-09-26 | — | — | WO | claimed |