SCHEMBL24618564

SCHEMBL24618564

OC1(c2ccc(Cl)cc2-c2ccccc2Cl)C2CC3CC(C2)C1C3

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 5/20 0.43
LMNA P02545 1/20 0.36
PGR P06401 1/20 0.36
PTPN1 P18031 1/20 0.34
ALDH1A1 P00352 1/20 0.33
CHRM2 P08172 1/20 0.32
ADRA2A P08913 1/20 0.32
OPRK1 P41145 1/20 0.32
PDE4D Q08499 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
GABRP O00591 1/20 0.32
GABRD O14764 1/20 0.32
GABRA1 P14867 1/20 0.32
GABRB1 P18505 1/20 0.32
GABRG2 P18507 1/20 0.32
GABRB3 P28472 1/20 0.32
GABRA5 P31644 1/20 0.32
GABRA3 P34903 1/20 0.32
GABRA2 P47869 1/20 0.32
GABRB2 P47870 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24618559 0.89 PDK2 (0.48) PDK2LMNAPGRPTPN1ALDH1A1
SCHEMBL24316335 0.86 HSD11B1 (0.33) PDK2LMNAALDH1A1SMN1; SMN2CXCR3
SCHEMBL23626209 0.81 PDK2 (0.34) PDK2
SCHEMBL24618107 0.78 PDK2 (0.48) PDK2LMNAPGRHSD11B1
SCHEMBL25961947 0.77 PDK2 (0.32) PDK2HSD11B1
SCHEMBL22797306 0.77 PDK2 (0.43) PDK2HSD11B1
SCHEMBL25962012 0.76 PDK2 (0.46) PDK2LMNAMEN1KMT2AHSD11B1
SCHEMBL23609917 0.76 PDK2 (0.49) PDK2LMNAPGRPTPN1CHRM2
SCHEMBL23319128 0.76 PDK2 (0.44) PDK2LMNASMN1; SMN2KMT2AHSD11B1
SCHEMBL25054783 0.76 PDK2 (0.44) PDK2LMNASMN1; SMN2KMT2AHSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220223796-A1 ORGANIC COMPOUND, ELECTRONIC COMPONENT CONTAINING ORGANIC COMPOUND, AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2022-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220223796-A1 ORGANIC COMPOUND, ELECTRONIC COMPONENT CONTAINING ORGANIC COMPOUND, AND ELECTRONIC DEVICE EXOC1, EXOC4, CHRM1 PDK2 2798/4885LMNA 621/4885PGR 2212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.