Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.69 |
| ▸ | TP53 | P04637 | 7/20 | 0.69 |
| ▸ | THRB | P10828 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30086031 | 0.91 | MAPT (0.83) | MAPTTP53THRBPOLBSMN1; SMN2 | |
| SCHEMBL24619745 | 0.91 | MAPT (0.83) | MAPTTP53THRBPOLBSMN1; SMN2 | |
| SCHEMBL30086042 | 0.89 | MAPT (0.71) | MAPTTP53THRBPOLBSMN1; SMN2 | |
| SCHEMBL24619236 | 0.89 | MAPT (0.71) | MAPTTP53THRBPOLBSMN1; SMN2 | |
| SCHEMBL29925013 | 0.88 | MAPT (0.70) | MAPTTP53THRBPOLBSMN1; SMN2 | |
| SCHEMBL29925486 | 0.88 | MAPT (0.70) | MAPTTP53THRBPOLBSMN1; SMN2 | |
| SCHEMBL24619434 | 0.88 | MAPT (0.70) | MAPTTP53THRBPOLBSMN1; SMN2 | |
| SCHEMBL24740806 | 0.88 | MAPT (0.70) | MAPTTP53THRBPOLBSMN1; SMN2 | |
| SCHEMBL24619882 | 0.88 | MAPT (0.69) | MAPTTP53THRBPOLBSMN1; SMN2 | |
| SCHEMBL29924843 | 0.88 | MAPT (0.69) | MAPTTP53THRBPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022150316-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2022-07-14 | — | — | WO | disclosed |