SCHEMBL24740806

SCHEMBL24740806

Cc1cccc(-c2cn3c(n2)sc2cc(C(=O)NCCCN4CCS(=O)(=O)CC4)ccc23)c1

nearest known ligand 0.72

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 7/20 0.70
▸ TP53 P04637 7/20 0.70
▸ POLB P06746 1/20 0.64
▸ SMN1; SMN2 Q16637 1/20 0.64
▸ THRB P10828 2/20 0.63
▸ LMNA P02545 2/20 0.59
▸ SLC2A1 P11166 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29925486 1.00 MAPT (0.70) MAPTTP53POLBSMN1; SMN2THRB
SCHEMBL24619745 0.92 MAPT (0.83) MAPTTP53POLBSMN1; SMN2THRB
SCHEMBL30086031 0.92 MAPT (0.83) MAPTTP53POLBSMN1; SMN2THRB
SCHEMBL30086042 0.90 MAPT (0.71) MAPTTP53POLBSMN1; SMN2THRB
SCHEMBL24619236 0.90 MAPT (0.71) MAPTTP53POLBSMN1; SMN2THRB
SCHEMBL24619434 0.89 MAPT (0.70) MAPTTP53POLBSMN1; SMN2THRB
SCHEMBL29925013 0.89 MAPT (0.70) MAPTTP53POLBSMN1; SMN2THRB
SCHEMBL24619451 0.88 MAPT (0.69) MAPTTP53POLBSMN1; SMN2THRB
SCHEMBL24619882 0.88 MAPT (0.69) MAPTTP53POLBSMN1; SMN2THRB
SCHEMBL29924843 0.88 MAPT (0.69) MAPTTP53POLBSMN1; SMN2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024010762-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2024-01-11 — — WO disclosed
US-20220370431-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2022-11-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220370431-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 MAPT 3215/4885TP53 96/4885POLB 1476/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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