Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.60 |
| ▸ | TP53 | P04637 | 4/20 | 0.58 |
| ▸ | THRB | P10828 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24740974 | 0.90 | MAPT (0.65) | MAPTTP53THRBLMNAPOLB | |
| SCHEMBL24105973 | 0.84 | MAPT (0.84) | MAPTTP53THRBLMNAPOLB | |
| SCHEMBL24619396 | 0.81 | TP53 (0.73) | MAPTTP53THRBLMNAPOLB | |
| SCHEMBL30086042 | 0.79 | MAPT (0.71) | MAPTTP53THRBLMNAPOLB | |
| SCHEMBL24619236 | 0.79 | MAPT (0.71) | MAPTTP53THRBLMNAPOLB | |
| SCHEMBL75315 | 0.79 | FLT3 (0.76) | — | |
| Hydrochloric Acid SCHEMBL74908 | 0.78 | FLT3 (0.75) | — | |
| SCHEMBL24740975 | 0.78 | LMNA (0.59) | MAPTTP53THRBLMNAPOLB | |
| SCHEMBL24105974 | 0.78 | MAPT (0.73) | MAPTTP53THRBPOLBSMN1; SMN2 | |
| SCHEMBL24741002 | 0.77 | MAPT (0.84) | MAPTTP53THRBLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022150316-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2022-07-14 | — | — | WO | disclosed |