Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29727245 | 1.00 | KDM4E (0.36) | KDM4EALDH1A1HPGDL3MBTL1IDO1 | |
| SCHEMBL24619157 | 0.83 | PSMD14 (0.42) | KDM4EROCK1GSK3AGSK3BDGAT1 | |
| SCHEMBL29727230 | 0.83 | PSMD14 (0.42) | KDM4EROCK1GSK3AGSK3BDGAT1 | |
| SCHEMBL29684436 | 0.82 | IDO1 (0.33) | IDO1TDO2ROCK1EGFR | |
| SCHEMBL24619125 | 0.82 | IDO1 (0.33) | IDO1TDO2ROCK1EGFR | |
| SCHEMBL27433795 | 0.79 | ROCK1 (0.37) | ROCK1DGAT1PDGFRBKDRBACE1 | |
| SCHEMBL17069695 | 0.77 | KDM4E (0.38) | KDM4EALDH1A1HPGDL3MBTL1DGAT1 | |
| SCHEMBL26630556 | 0.77 | ROCK1 (0.38) | KDM4EALDH1A1HPGDROCK1DGAT1 | |
| SCHEMBL24619120 | 0.77 | IDO1 (0.33) | IDO1TDO2ROCK1EGFR | |
| SCHEMBL24619653 | 0.77 | KDM4E (0.43) | KDM4EALDH1A1HPGDL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149057-A1 | CDK INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2022-07-14 | — | — | WO | disclosed |