Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 3/20 | 0.38 |
| ▸ | ACACA | Q13085 | 3/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395918 | 0.79 | KDM4E (0.52) | KDM4EMAPK1HIF1ASIGMAR1ACACB | |
| SCHEMBL8392313 | 0.79 | KDM4E (0.52) | KDM4EMAPK1HIF1ASIGMAR1ACACB | |
| SCHEMBL8392406 | 0.77 | KDM4E (0.50) | KDM4EMAPK1HIF1ASIGMAR1ACACB | |
| SCHEMBL8392716 | 0.77 | KDM4E (0.50) | KDM4EMAPK1HIF1ASIGMAR1ACACB | |
| SCHEMBL24289082 | 0.75 | — | — | |
| SCHEMBL8392280 | 0.75 | KDM4E (0.56) | KDM4EMAPK1HIF1ASIGMAR1ACACB | |
| SCHEMBL9998117 | 0.73 | KDM4E (0.45) | KDM4EMAPK1HIF1ASIGMAR1ACACB | |
| SCHEMBL19731592 | 0.73 | SIGMAR1 (0.56) | KDM4EMAPK1HIF1ASIGMAR1PAOX | |
| SCHEMBL24115530 | 0.71 | SIGMAR1 (0.59) | KDM4EMAPK1HIF1ASIGMAR1PAOX | |
| SCHEMBL23471410 | 0.70 | KDM4E (0.60) | KDM4EMAPK1HIF1ASIGMAR1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149618-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | 中外製薬株式会社 | 2022-07-14 | — | — | WO | disclosed |