Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C2B | O00750 | 1/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 13/20 | 0.37 |
| ▸ | KRAS | P01116 | 12/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CD38 | P28907 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24625447 | 0.88 | SOS1 (0.37) | PIK3C2BSOS1KRASP2RX7LMNA | |
| SCHEMBL24625531 | 0.87 | CD38 (0.35) | SOS1KRASP2RX7LMNAEGFR | |
| SCHEMBL24625416 | 0.86 | EGFR (0.49) | LMNAEGFRTSHRHTTCYP3A4 | |
| SCHEMBL24625394 | 0.85 | SOS1 (0.40) | SOS1KRASCYP3A4CD38 | |
| SCHEMBL24625613 | 0.84 | CD38 (0.47) | PIK3C2BSOS1P2RX7CYP3A4CD38 | |
| SCHEMBL24625311 | 0.83 | CD38 (0.37) | PIK3C2BSOS1P2RX7LMNAEGFR | |
| SCHEMBL24625210 | 0.82 | CD38 (0.36) | PIK3C2BSOS1KRASP2RX7LMNA | |
| SCHEMBL24625163 | 0.81 | EGFR (0.39) | SOS1KRASP2RX7LMNAEGFR | |
| SCHEMBL24625393 | 0.81 | EGFR (0.40) | PIK3C2BSOS1KRASP2RX7LMNA | |
| SCHEMBL24625607 | 0.80 | SOS1 (0.41) | SOS1KRASP2RX7LMNAEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022148442-A1 | 6-SUBSTITUTED PHOSPHORYL QUINAZOLINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-07-14 | — | — | WO | disclosed |